Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1249/genes/?format=api
{ "data": [ { "type": "Gene", "id": "ROBO2", "attributes": { "go_molecular_function": [ "['axon guidance receptor activity', 'cell-cell adhesion mediator activity', 'identical protein binding', 'protein binding']" ], "pathway_id": [ "kegg_path:hsa04360", "R-HSA-1266738", "R-HSA-376176", "R-HSA-422475", "R-HSA-428542", "R-HSA-8985801", "R-HSA-9010553", "R-HSA-9010642", "R-HSA-9675108" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q9HCK4", "ensembl_id": "None", "entrez_id": "ENSG00000185008", "chromosome_number": "3", "lastmodified": "2024-02-29T15:02:20.959106" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3694" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ROBO2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ROBO2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1249" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ROBO2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ROBO2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ROBO2/?format=api" } }, { "type": "Gene", "id": "ROBO4", "attributes": { "go_molecular_function": [ "['signaling receptor activity', 'cell-cell adhesion mediator activity', 'protein binding']" ], "pathway_id": [], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q8WZ75", "ensembl_id": "None", "entrez_id": "ENSG00000154133", "chromosome_number": "11", "lastmodified": "2024-02-29T15:02:20.963465" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3695" }, { "type": "SmallVariant", "id": "3696" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ROBO4/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ROBO4/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "1249" }, { "type": "GeneCombination", "id": "1250" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ROBO4/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ROBO4/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ROBO4/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2024 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }