Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1228/genes/?format=api
{ "data": [ { "type": "Gene", "id": "IL10RA", "attributes": { "go_molecular_function": [ "['signaling receptor activity', 'interleukin-10 binding', 'cytokine receptor activity', 'protein binding', 'interleukin-10 receptor activity']" ], "pathway_id": [ "kegg_path:hsa04060", "kegg_path:hsa04061", "kegg_path:hsa04630", "kegg_path:hsa05145", "kegg_path:hsa05152", "kegg_path:hsa05163", "R-HSA-1280215", "R-HSA-168256", "R-HSA-449147", "R-HSA-6783783" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q13651", "ensembl_id": "None", "entrez_id": "ENSG00000110324", "chromosome_number": "11", "lastmodified": "2021-10-18T11:00:44.547062" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "270" }, { "type": "SmallVariant", "id": "271" }, { "type": "SmallVariant", "id": "3642" }, { "type": "SmallVariant", "id": "3647" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/IL10RA/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/IL10RA/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "97" }, { "type": "GeneCombination", "id": "1226" }, { "type": "GeneCombination", "id": "1228" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/IL10RA/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/IL10RA/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/IL10RA/?format=api" } }, { "type": "Gene", "id": "IL10RB", "attributes": { "go_molecular_function": [ "['signaling receptor activity', 'cytokine receptor activity', 'protein binding', 'interleukin-10 receptor activity']" ], "pathway_id": [ "kegg_path:hsa04060", "kegg_path:hsa04061", "kegg_path:hsa04630", "kegg_path:hsa05145", "kegg_path:hsa05152", "kegg_path:hsa05163", "R-HSA-1280215", "R-HSA-168256", "R-HSA-449147", "R-HSA-449836", "R-HSA-6783783", "R-HSA-8854691" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q08334", "ensembl_id": "None", "entrez_id": "ENSG00000243646", "chromosome_number": "21", "lastmodified": "2024-02-29T15:02:20.827002" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3648" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/IL10RB/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/IL10RB/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1228" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/IL10RB/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/IL10RB/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/IL10RB/?format=api" } }, { "type": "Gene", "id": "LRBA", "attributes": { "go_molecular_function": [ "['molecular_function', 'protein kinase binding']" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "P50851", "ensembl_id": "None", "entrez_id": "ENSG00000198589", "chromosome_number": "4", "lastmodified": "2021-10-18T11:00:44.666340" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "51" }, { "type": "SmallVariant", "id": "3633" }, { "type": "SmallVariant", "id": "3646" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LRBA/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LRBA/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "21" }, { "type": "GeneCombination", "id": "1222" }, { "type": "GeneCombination", "id": "1228" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LRBA/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LRBA/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/LRBA/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }