Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1221/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CD8A", "attributes": { "go_molecular_function": [ "['MHC class I protein complex binding', 'protein kinase binding', 'protein binding', 'MHC class I protein binding', 'coreceptor activity']" ], "pathway_id": [ "kegg_path:hsa04514", "kegg_path:hsa04612", "kegg_path:hsa04640", "kegg_path:hsa04660", "kegg_path:hsa05135", "kegg_path:hsa05340", "R-HSA-1280218", "R-HSA-168256", "R-HSA-198933", "kegg_path:hsa04514", "kegg_path:hsa04612", "kegg_path:hsa04640", "kegg_path:hsa04660", "kegg_path:hsa05135", "kegg_path:hsa05340" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P01732", "ensembl_id": "None", "entrez_id": "ENSG00000153563", "chromosome_number": "2", "lastmodified": "2024-02-29T15:02:20.767058" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3630" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CD8A/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CD8A/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1221" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CD8A/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CD8A/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CD8A/?format=api" } }, { "type": "Gene", "id": "PIK3R1", "attributes": { "go_molecular_function": [ "['phosphatidylinositol 3-kinase binding', 'insulin receptor binding', 'insulin binding', 'neurotrophin TRKA receptor binding', 'insulin-like growth factor receptor binding', 'phosphatidylinositol 3-kinase regulator activity', 'phosphotyrosine residue binding', 'ErbB-3 class receptor binding', 'protein heterodimerization activity', 'protein binding', 'protein phosphatase binding', 'transmembrane receptor protein tyrosine kinase adaptor activity', '1-phosphatidylinositol-3-kinase regulator activity', 'phosphatidylinositol 3-kinase regulatory subunit binding', 'insulin receptor substrate binding']" ], "pathway_id": [ "kegg_path:hsa01521", "kegg_path:hsa01522", "kegg_path:hsa01524", "kegg_path:hsa04012", "kegg_path:hsa04014", "kegg_path:hsa04015", "kegg_path:hsa04024", "kegg_path:hsa04062", "kegg_path:hsa04066", "kegg_path:hsa04068", "kegg_path:hsa04070", "kegg_path:hsa04071", "kegg_path:hsa04072", "kegg_path:hsa04140", "kegg_path:hsa04150", "kegg_path:hsa04151", "kegg_path:hsa04152", "kegg_path:hsa04210", "kegg_path:hsa04211", "kegg_path:hsa04213", "kegg_path:hsa04218", "kegg_path:hsa04360", "kegg_path:hsa04370", "kegg_path:hsa04380", "kegg_path:hsa04510", "kegg_path:hsa04550", "kegg_path:hsa04611", "kegg_path:hsa04613", "kegg_path:hsa04620", "kegg_path:hsa04625", "kegg_path:hsa04630", "kegg_path:hsa04650", "kegg_path:hsa04660", "kegg_path:hsa04662", "kegg_path:hsa04664", "kegg_path:hsa04666", "kegg_path:hsa04668", "kegg_path:hsa04670", "kegg_path:hsa04722", "kegg_path:hsa04725", "kegg_path:hsa04750", "kegg_path:hsa04810", "kegg_path:hsa04910", "kegg_path:hsa04914", "kegg_path:hsa04915", "kegg_path:hsa04917", "kegg_path:hsa04919", "kegg_path:hsa04923", "kegg_path:hsa04926", "kegg_path:hsa04929", "kegg_path:hsa04930", "kegg_path:hsa04931", "kegg_path:hsa04932", "kegg_path:hsa04933", "kegg_path:hsa04935", "kegg_path:hsa04960", "kegg_path:hsa04973", "kegg_path:hsa05010", "kegg_path:hsa05017", "kegg_path:hsa05020", "kegg_path:hsa05100", "kegg_path:hsa05131", "kegg_path:hsa05135", "kegg_path:hsa05142", "kegg_path:hsa05146", "kegg_path:hsa05160", "kegg_path:hsa05161", "kegg_path:hsa05162", "kegg_path:hsa05163", "kegg_path:hsa05164", "kegg_path:hsa05165", "kegg_path:hsa05166", "kegg_path:hsa05167", "kegg_path:hsa05168", "kegg_path:hsa05169", "kegg_path:hsa05170", "kegg_path:hsa05171", "kegg_path:hsa05200", "kegg_path:hsa05203", "kegg_path:hsa05205", "kegg_path:hsa05206", "kegg_path:hsa05210", "kegg_path:hsa05211", "kegg_path:hsa05212", "kegg_path:hsa05213", "kegg_path:hsa05214", "kegg_path:hsa05215", "kegg_path:hsa05218", "kegg_path:hsa05220", "kegg_path:hsa05221", "kegg_path:hsa05222", "kegg_path:hsa05223", "kegg_path:hsa05224", "kegg_path:hsa05225", "kegg_path:hsa05226", "kegg_path:hsa05230", "kegg_path:hsa05231", "kegg_path:hsa05235", "kegg_path:hsa05418", "kegg_path:hsa01521", "kegg_path:hsa01522", "kegg_path:hsa01524", "kegg_path:hsa04012", "kegg_path:hsa04014", "kegg_path:hsa04015", "kegg_path:hsa04024", "kegg_path:hsa04062", "kegg_path:hsa04066", "kegg_path:hsa04068", "kegg_path:hsa04070", "kegg_path:hsa04071", "kegg_path:hsa04072", "kegg_path:hsa04140", "kegg_path:hsa04150", "kegg_path:hsa04151", "kegg_path:hsa04152", "kegg_path:hsa04210", "kegg_path:hsa04211", "kegg_path:hsa04213", "kegg_path:hsa04218", "kegg_path:hsa04360", "kegg_path:hsa04370", "kegg_path:hsa04380", "kegg_path:hsa04510", "kegg_path:hsa04550", "kegg_path:hsa04611", "kegg_path:hsa04613", "kegg_path:hsa04620", "kegg_path:hsa04625", "kegg_path:hsa04630", "kegg_path:hsa04650", "kegg_path:hsa04660", "kegg_path:hsa04662", "kegg_path:hsa04664", "kegg_path:hsa04666", "kegg_path:hsa04668", "kegg_path:hsa04670", "kegg_path:hsa04722", "kegg_path:hsa04725", "kegg_path:hsa04750", "kegg_path:hsa04810", "kegg_path:hsa04910", "kegg_path:hsa04914", "kegg_path:hsa04915", "kegg_path:hsa04917", "kegg_path:hsa04919", "kegg_path:hsa04923", "kegg_path:hsa04926", "kegg_path:hsa04929", "kegg_path:hsa04930", "kegg_path:hsa04931", "kegg_path:hsa04932", "kegg_path:hsa04933", "kegg_path:hsa04935", "kegg_path:hsa04960", "kegg_path:hsa04973", "kegg_path:hsa05010", "kegg_path:hsa05017", "kegg_path:hsa05020", "kegg_path:hsa05100", "kegg_path:hsa05131", "kegg_path:hsa05135", "kegg_path:hsa05142", "kegg_path:hsa05146", "kegg_path:hsa05160", "kegg_path:hsa05161", "kegg_path:hsa05162", "kegg_path:hsa05163", "kegg_path:hsa05164", "kegg_path:hsa05165", "kegg_path:hsa05166", "kegg_path:hsa05167", "kegg_path:hsa05168", "kegg_path:hsa05169", "kegg_path:hsa05170", "kegg_path:hsa05171", "kegg_path:hsa05200", "kegg_path:hsa05203", "kegg_path:hsa05205", "kegg_path:hsa05206", "kegg_path:hsa05210", "kegg_path:hsa05211", "kegg_path:hsa05212", "kegg_path:hsa05213", "kegg_path:hsa05214", "kegg_path:hsa05215", "kegg_path:hsa05218", "kegg_path:hsa05220", "kegg_path:hsa05221", "kegg_path:hsa05222", "kegg_path:hsa05223", "kegg_path:hsa05224", "kegg_path:hsa05225", "kegg_path:hsa05226", "kegg_path:hsa05230", "kegg_path:hsa05231", "kegg_path:hsa05235", "kegg_path:hsa05418", "R-HSA-109582", "R-HSA-109704", "R-HSA-112399", "R-HSA-114604", "R-HSA-1226099", "R-HSA-1227986", "R-HSA-1227990", "R-HSA-1236382", "R-HSA-1236394", "R-HSA-1250342", "R-HSA-1257604", "R-HSA-1266695", "R-HSA-1266738", "R-HSA-1280215", "R-HSA-1280218", "R-HSA-1430728", "R-HSA-1433557", "R-HSA-1483255", "R-HSA-1483257", "R-HSA-1500931", "R-HSA-162582", "R-HSA-1643685", "R-HSA-1643713", "R-HSA-1660499", "R-HSA-166520", "R-HSA-168249", "R-HSA-168256", "R-HSA-177929", "R-HSA-180292", "R-HSA-1839117", "R-HSA-1839124", "R-HSA-186763", "R-HSA-186797", "R-HSA-187037", "R-HSA-190236", "R-HSA-194138", "R-HSA-1963642", "R-HSA-198203", "R-HSA-199418", "R-HSA-202403", "R-HSA-202424", "R-HSA-202733", "R-HSA-2029480", "R-HSA-2029485", "R-HSA-210993", "R-HSA-2172127", "R-HSA-2219528", "R-HSA-2219530", "R-HSA-2404192", "R-HSA-2424491", "R-HSA-2428924", "R-HSA-2428928", "R-HSA-2454202", "R-HSA-2730905", "R-HSA-372790", "R-HSA-373753", "R-HSA-388396", "R-HSA-388841", "R-HSA-389356", "R-HSA-389357", "R-HSA-416476", "R-HSA-422475", "R-HSA-430116", "R-HSA-4420097", "R-HSA-449147", "R-HSA-451927", "R-HSA-512988", "R-HSA-556833", "R-HSA-5637810", "R-HSA-5637812", "R-HSA-5637815", "R-HSA-5654687", "R-HSA-5654689", "R-HSA-5654695", "R-HSA-5654696", "R-HSA-5654708", "R-HSA-5654710", "R-HSA-5654716", "R-HSA-5654720", "R-HSA-5654736", "R-HSA-5654738", "R-HSA-5654741", "R-HSA-5654743", "R-HSA-5655253", "R-HSA-5655291", "R-HSA-5655302", "R-HSA-5655332", "R-HSA-5663202", "R-HSA-5673001", "R-HSA-5683057", "R-HSA-5684996", "R-HSA-6785807", "R-HSA-6806834", "R-HSA-6811558", "R-HSA-74751", "R-HSA-74752", "R-HSA-76002", "R-HSA-8851907", "R-HSA-8853334", "R-HSA-8853338", "R-HSA-8853659", "R-HSA-8939211", "R-HSA-9006115", "R-HSA-9006335", "R-HSA-9006925", "R-HSA-9006931", "R-HSA-9006934", "R-HSA-9009391", "R-HSA-9027276", "R-HSA-9028335", "R-HSA-9034015", "R-HSA-912526", "R-HSA-912631", "R-HSA-9603381", "R-HSA-9607240", "R-HSA-9664565", "R-HSA-9665348", "R-HSA-9669938", "R-HSA-9670439", "R-HSA-9671555", "R-HSA-9673767", "R-HSA-9673770", "R-HSA-9675108", "R-HSA-9682385", "R-HSA-9703465", "R-HSA-9703648", "R-HSA-983695", "R-HSA-983705" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P27986", "ensembl_id": "None", "entrez_id": "ENSG00000145675", "chromosome_number": "5", "lastmodified": "2024-02-29T15:02:20.771438" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3631" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PIK3R1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PIK3R1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1221" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PIK3R1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PIK3R1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PIK3R1/?format=api" } }, { "type": "Gene", "id": "TNFRSF13B", "attributes": { "go_molecular_function": [ "['signaling receptor activity', 'protein binding']" ], "pathway_id": [ "kegg_path:hsa04060", "kegg_path:hsa04672", "kegg_path:hsa05340", "R-HSA-1280215", "R-HSA-168256", "R-HSA-5668541", "R-HSA-5669034" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "O14836", "ensembl_id": "None", "entrez_id": "ENSG00000240505", "chromosome_number": "17", "lastmodified": "2021-10-18T11:00:44.943076" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "149" }, { "type": "SmallVariant", "id": "3632" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TNFRSF13B/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TNFRSF13B/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "54" }, { "type": "GeneCombination", "id": "1221" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TNFRSF13B/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TNFRSF13B/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TNFRSF13B/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }