Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1205/genes/?format=api
{ "data": [ { "type": "Gene", "id": "COL8A2", "attributes": { "go_molecular_function": [ "['protein-macromolecule adaptor activity', 'extracellular matrix structural constituent conferring tensile strength', 'extracellular matrix structural constituent']" ], "pathway_id": [ "kegg_path:hsa04974", "R-HSA-1442490", "R-HSA-1474228", "R-HSA-1474244", "R-HSA-1474290", "R-HSA-1650814", "R-HSA-2022090", "R-HSA-216083", "R-HSA-8948216" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P25067", "ensembl_id": "None", "entrez_id": "ENSG00000171812", "chromosome_number": "1", "lastmodified": "2024-02-29T15:02:20.485846" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3519" }, { "type": "SmallVariant", "id": "3581" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/COL8A2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/COL8A2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "1186" }, { "type": "GeneCombination", "id": "1205" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/COL8A2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/COL8A2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/COL8A2/?format=api" } }, { "type": "Gene", "id": "GALNT14", "attributes": { "go_molecular_function": [ "['metal ion binding', 'polypeptide N-acetylgalactosaminyltransferase activity', 'carbohydrate binding']" ], "pathway_id": [ "kegg_path:hsa00512", "kegg_path:hsa00514", "kegg_path:hsa01100", "R-HSA-392499", "R-HSA-5173105", "R-HSA-597592", "R-HSA-913709" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q96FL9", "ensembl_id": "None", "entrez_id": "ENSG00000158089", "chromosome_number": "2", "lastmodified": "2024-02-29T15:02:20.629064" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3580" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GALNT14/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GALNT14/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1205" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GALNT14/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GALNT14/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/GALNT14/?format=api" } }, { "type": "Gene", "id": "IPO5", "attributes": { "go_molecular_function": [ "['small GTPase binding', 'protein binding', 'RNA binding', 'nuclear localization sequence binding', 'nuclear import signal receptor activity', 'GTPase inhibitor activity']" ], "pathway_id": [ "R-HSA-1643685", "R-HSA-168255", "R-HSA-168273", "R-HSA-192905", "R-HSA-5663205" ], "essential_gene": null, "status": "CU", "uniprot_acc": "O00410", "ensembl_id": "None", "entrez_id": "ENSG00000065150", "chromosome_number": "13", "lastmodified": "2024-02-29T15:02:20.625465" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3579" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/IPO5/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/IPO5/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1205" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/IPO5/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/IPO5/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/IPO5/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }