Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1188/genes/?format=api
{ "data": [ { "type": "Gene", "id": "PPIP5K2", "attributes": { "go_molecular_function": [ "['inositol hexakisphosphate kinase activity', 'diphosphoinositol-pentakisphosphate kinase activity', 'inositol hexakisphosphate 3-kinase activity', 'inositol hexakisphosphate 5-kinase activity', 'inositol heptakisphosphate kinase activity', 'inositol-1,3,4,5,6-pentakisphosphate kinase activity', 'inositol hexakisphosphate 1-kinase activity', '5-diphosphoinositol pentakisphosphate 3-kinase activity', 'ATP binding']" ], "pathway_id": [ "kegg_path:hsa04070", "R-HSA-1430728", "R-HSA-1483249", "R-HSA-1855167", "kegg_path:hsa04070", "R-HSA-1430728", "R-HSA-1483249", "R-HSA-1855167" ], "essential_gene": null, "status": "CU", "uniprot_acc": "O43314", "ensembl_id": "None", "entrez_id": "ENSG00000145725", "chromosome_number": "5", "lastmodified": "2024-02-29T15:02:20.496393" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3523" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PPIP5K2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PPIP5K2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1188" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PPIP5K2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PPIP5K2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PPIP5K2/?format=api" } }, { "type": "Gene", "id": "SLC8A3", "attributes": { "go_molecular_function": [ "['calmodulin binding', 'cation:cation antiporter activity', 'ion antiporter activity involved in regulation of postsynaptic membrane potential', 'calcium:sodium antiporter activity', 'metal ion binding']" ], "pathway_id": [ "kegg_path:hsa04020", "kegg_path:hsa04022", "kegg_path:hsa04260", "kegg_path:hsa04261", "kegg_path:hsa04371", "kegg_path:hsa04740", "kegg_path:hsa04961", "kegg_path:hsa04974", "kegg_path:hsa04978", "kegg_path:hsa05410", "kegg_path:hsa05412", "kegg_path:hsa05414", "R-HSA-109582", "R-HSA-382551", "R-HSA-397014", "R-HSA-418346", "R-HSA-418359", "R-HSA-418360", "R-HSA-425393", "R-HSA-425407", "R-HSA-425561", "R-HSA-5576891", "R-HSA-5578775", "R-HSA-8949215" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P57103", "ensembl_id": "None", "entrez_id": "ENSG00000100678", "chromosome_number": "14", "lastmodified": "2024-02-29T15:02:20.500185" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3524" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SLC8A3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SLC8A3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1188" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SLC8A3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SLC8A3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SLC8A3/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }