Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1187/genes/?format=api
{ "data": [ { "type": "Gene", "id": "LOXL2", "attributes": { "go_molecular_function": [ "['scavenger receptor activity', 'oligosaccharide binding', 'calcium ion binding', 'electron transfer activity', 'protein binding', 'protein-lysine 6-oxidase activity', 'copper ion binding']" ], "pathway_id": [ "R-HSA-1474244", "R-HSA-1474290", "R-HSA-1566948", "R-HSA-2022090", "R-HSA-2243919" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q9Y4K0", "ensembl_id": "None", "entrez_id": "ENSG00000134013", "chromosome_number": "8", "lastmodified": "2024-02-29T15:02:20.492784" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3522" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LOXL2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LOXL2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1187" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LOXL2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LOXL2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/LOXL2/?format=api" } }, { "type": "Gene", "id": "PIKFYVE", "attributes": { "go_molecular_function": [ "['zinc ion binding', 'phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity', 'protein serine/threonine/tyrosine kinase activity', 'protein binding', 'ATP hydrolysis activity', '1-phosphatidylinositol-3-phosphate 5-kinase activity', 'protein serine/threonine kinase activity', '1-phosphatidylinositol-4-phosphate 5-kinase activity', '1-phosphatidylinositol-5-kinase activity', 'protein serine kinase activity', 'ATP binding']" ], "pathway_id": [ "kegg_path:hsa00562", "kegg_path:hsa01100", "kegg_path:hsa04070", "kegg_path:hsa04145", "kegg_path:hsa04810", "R-HSA-1430728", "R-HSA-1483255", "R-HSA-1483257", "R-HSA-1660514", "R-HSA-1660516", "R-HSA-1660517", "R-HSA-556833" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q9Y2I7", "ensembl_id": "None", "entrez_id": "ENSG00000115020", "chromosome_number": "2", "lastmodified": "2024-02-29T15:02:20.489352" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3521" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PIKFYVE/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PIKFYVE/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1187" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PIKFYVE/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PIKFYVE/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PIKFYVE/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }