Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/genecombinations/117/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI166", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 3, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 3, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 2 }, "omim_id": [ "OMIM220100" ], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:40.196868" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "214" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI166/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI166/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "332" }, { "type": "SmallVariant", "id": "333" }, { "type": "SmallVariant", "id": "334" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI166/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI166/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "715" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI166/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI166/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI166/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI166/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "117" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI166/?format=api" } }, { "type": "Combination", "id": "OLI178", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 3, "functional_gene_evidence_manual_harmonized": 3, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 3, "functional_variant_evidence_manual": 2, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 2, "functional_final_manual": 3, "functional_final_metascore": 3, "final_manual": 3, "final_metascore": 3 }, "omim_id": [ "OMIM220100" ], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:40.410723" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "214" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI178/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI178/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "333" }, { "type": "SmallVariant", "id": "334" }, { "type": "SmallVariant", "id": "352" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI178/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI178/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "633" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI178/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI178/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI178/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI178/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "117" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI178/?format=api" } }, { "type": "Combination", "id": "OLI179", "attributes": { "scores": { "familial_evidence": 3, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 3, "functional_gene_evidence_manual_harmonized": 3, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 3, "functional_variant_evidence_manual": 3, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 3, "functional_final_manual": 3, "functional_final_metascore": 3, "final_manual": 3, "final_metascore": 3 }, "omim_id": [ "OMIM220100" ], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:40.426511" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "214" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI179/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI179/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "333" }, { "type": "SmallVariant", "id": "334" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI179/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI179/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "633" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI179/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI179/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI179/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI179/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "117" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI179/?format=api" } }, { "type": "Combination", "id": "OLI180", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 3, "functional_gene_evidence_manual_harmonized": 3, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 3, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 1, "final_metascore": 1 }, "omim_id": [ "OMIM220100" ], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:40.444721" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "214" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI180/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI180/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "333" }, { "type": "SmallVariant", "id": "353" }, { "type": "SmallVariant", "id": "354" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI180/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI180/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "633" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI180/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI180/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI180/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI180/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "117" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI180/?format=api" } }, { "type": "Combination", "id": "OLI181", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 3, "functional_gene_evidence_manual_harmonized": 3, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 3, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 1, "final_metascore": 1 }, "omim_id": [ "OMIM220100" ], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:40.459161" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "214" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI181/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI181/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "333" }, { "type": "SmallVariant", "id": "354" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI181/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI181/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "633" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI181/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI181/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI181/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI181/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "117" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI181/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 5 } }