Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1149/genes/?format=api
{ "data": [ { "type": "Gene", "id": "C9orf72", "attributes": { "go_molecular_function": [ "guanyl-nucleotide exchange factor activity", "small GTPase binding", "protein binding" ], "pathway_id": [ "kegg_path:hsa04140", "kegg_path:hsa05014", "kegg_path:hsa05022" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q96LT7", "ensembl_id": "None", "entrez_id": "ENSG00000147894", "chromosome_number": "9", "lastmodified": "2021-10-18T11:00:44.423366" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "CopyNumberVariant", "id": "530" }, { "type": "CopyNumberVariant", "id": "1225" }, { "type": "CopyNumberVariant", "id": "1694" }, { "type": "CopyNumberVariant", "id": "1808" }, { "type": "CopyNumberVariant", "id": "3061" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/C9orf72/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/C9orf72/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 25 }, "data": [ { "type": "GeneCombination", "id": "175" }, { "type": "GeneCombination", "id": "176" }, { "type": "GeneCombination", "id": "177" }, { "type": "GeneCombination", "id": "377" }, { "type": "GeneCombination", "id": "390" }, { "type": "GeneCombination", "id": "413" }, { "type": "GeneCombination", "id": "428" }, { "type": "GeneCombination", "id": "429" }, { "type": "GeneCombination", "id": "430" }, { "type": "GeneCombination", "id": "431" }, { "type": "GeneCombination", "id": "432" }, { "type": "GeneCombination", "id": "433" }, { "type": "GeneCombination", "id": "435" }, { "type": "GeneCombination", "id": "449" }, { "type": "GeneCombination", "id": "450" }, { "type": "GeneCombination", "id": "552" }, { "type": "GeneCombination", "id": "556" }, { "type": "GeneCombination", "id": "557" }, { "type": "GeneCombination", "id": "558" }, { "type": "GeneCombination", "id": "600" }, { "type": "GeneCombination", "id": "603" }, { "type": "GeneCombination", "id": "553" }, { "type": "GeneCombination", "id": "1147" }, { "type": "GeneCombination", "id": "1148" }, { "type": "GeneCombination", "id": "1149" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/C9orf72/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/C9orf72/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/C9orf72/?format=api" } }, { "type": "Gene", "id": "MAPT", "attributes": { "go_molecular_function": [ "['enzyme binding', 'single-stranded DNA binding', 'histone-dependent DNA binding', 'double-stranded DNA binding', 'sequence-specific DNA binding', 'minor groove of adenine-thymine-rich DNA binding', 'SH3 domain binding', 'Hsp90 protein binding', 'protein kinase binding', 'lipoprotein particle binding', 'RNA binding', 'dynactin binding', 'protein phosphatase 2A binding', 'identical protein binding', 'microtubule binding', 'phosphatidylinositol binding', 'chaperone binding', 'phosphatidylinositol bisphosphate binding', 'DNA binding', 'protein-macromolecule adaptor activity', 'apolipoprotein binding', 'protein binding', 'microtubule lateral binding', 'actin binding']" ], "pathway_id": [ "kegg_path:hsa04010", "kegg_path:hsa05010", "kegg_path:hsa05012", "kegg_path:hsa05022", "kegg_path:hsa04010", "kegg_path:hsa05010", "kegg_path:hsa05012", "kegg_path:hsa05022", "R-HSA-109581", "R-HSA-111465", "R-HSA-264870", "R-HSA-5357801", "R-HSA-75153" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P10636", "ensembl_id": "None", "entrez_id": "ENSG00000186868", "chromosome_number": "17", "lastmodified": "2021-10-18T11:00:44.827622" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "1435" }, { "type": "SmallVariant", "id": "1441" }, { "type": "SmallVariant", "id": "3098" }, { "type": "SmallVariant", "id": "3423" }, { "type": "SmallVariant", "id": "3438" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MAPT/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MAPT/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 6 }, "data": [ { "type": "GeneCombination", "id": "454" }, { "type": "GeneCombination", "id": "457" }, { "type": "GeneCombination", "id": "1038" }, { "type": "GeneCombination", "id": "1039" }, { "type": "GeneCombination", "id": "1149" }, { "type": "GeneCombination", "id": "1153" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MAPT/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MAPT/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MAPT/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }