Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1142/genes/?format=api
{ "data": [ { "type": "Gene", "id": "GRHPR", "attributes": { "go_molecular_function": [ "['protein homodimerization activity', 'NADPH binding', 'glyoxylate reductase (NADP+) activity', 'glycerate dehydrogenase activity', 'protein binding', 'hydroxypyruvate reductase activity', 'NAD binding', 'carboxylic acid binding']" ], "pathway_id": [ "kegg_path:hsa00260", "kegg_path:hsa00620", "kegg_path:hsa00630", "kegg_path:hsa01100", "R-HSA-1430728", "R-HSA-389661", "R-HSA-71291" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q9UBQ7", "ensembl_id": "None", "entrez_id": "ENSG00000137106", "chromosome_number": "9", "lastmodified": "2024-02-29T15:02:20.214766" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3405" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GRHPR/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GRHPR/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1142" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GRHPR/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GRHPR/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/GRHPR/?format=api" } }, { "type": "Gene", "id": "SLC4A1", "attributes": { "go_molecular_function": [ "['protein homodimerization activity', 'hemoglobin binding', 'anion transmembrane transporter activity', 'chloride transmembrane transporter activity', 'ankyrin binding', 'protein binding', 'bicarbonate transmembrane transporter activity', 'anion:anion antiporter activity', 'transmembrane transporter activity', 'protein-membrane adaptor activity', 'inorganic anion exchanger activity']" ], "pathway_id": [ "kegg_path:hsa04966", "R-HSA-1237044", "R-HSA-1247673", "R-HSA-1480926", "R-HSA-1643685", "R-HSA-382551", "R-HSA-425381", "R-HSA-425393", "R-HSA-425407", "R-HSA-5619050", "R-HSA-5619102", "R-HSA-5619115" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P02730", "ensembl_id": "None", "entrez_id": "ENSG00000004939", "chromosome_number": "17", "lastmodified": "2024-02-29T15:02:20.207247" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "3402" }, { "type": "SmallVariant", "id": "3406" }, { "type": "SmallVariant", "id": "3407" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SLC4A1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SLC4A1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "1140" }, { "type": "GeneCombination", "id": "1142" }, { "type": "GeneCombination", "id": "1143" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SLC4A1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SLC4A1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SLC4A1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }