Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/114/genes/?format=api
{ "data": [ { "type": "Gene", "id": "P3H1", "attributes": { "go_molecular_function": [ "procollagen-proline 3-dioxygenase activity", "protein binding", "molecular_function", "collagen binding" ], "pathway_id": [ "R-HSA-1474290", "R-HSA-1650814", "R-HSA-1474244" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q32P28", "ensembl_id": "ENSG00000117385", "entrez_id": "64175", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.753128" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "318" }, { "type": "SmallVariant", "id": "319" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/P3H1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/P3H1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "114" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/P3H1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/P3H1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/P3H1/?format=api" } }, { "type": "Gene", "id": "WNT1", "attributes": { "go_molecular_function": [ "receptor ligand activity", "cytokine activity", "morphogen activity", "frizzled binding" ], "pathway_id": [ "R-HSA-500792", "R-HSA-162582", "R-HSA-372790", "kegg_path:hsa04310", "R-HSA-195721", "R-HSA-373080", "R-HSA-3238698", "kegg_path:hsa04916", "kegg_path:hsa05022", "kegg_path:hsa05200", "kegg_path:hsa05205", "R-HSA-3858494", "kegg_path:hsa04390", "kegg_path:hsa04934", "kegg_path:hsa04550", "kegg_path:hsa05165", "R-HSA-4086400", "kegg_path:hsa05010", "R-HSA-1266738", "kegg_path:hsa05226", "R-HSA-201681", "R-HSA-4641262", "kegg_path:hsa05217", "R-HSA-381340", "kegg_path:hsa05225", "kegg_path:hsa04150", "kegg_path:hsa05224" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P04628", "ensembl_id": "ENSG00000125084", "entrez_id": "7471", "chromosome_number": "12", "lastmodified": "2021-10-18T11:00:44.978016" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "321" }, { "type": "SmallVariant", "id": "320" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/WNT1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/WNT1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "114" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/WNT1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/WNT1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/WNT1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }