Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/genecombinations/1126/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI1582", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM620040", "OMIM224230", "OMIM613990", "OMIM616353", "OMIM613988", "OMIM615190", "OMIM613989", "OMIM613987", "OMIM305000", "OMIM127550" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2023-05-16T12:03:08.328058" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "1775" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1582/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1582/diseases/?format=api" } }, "variant_set": { "meta": { "count": 6 }, "data": [ { "type": "CopyNumberVariant", "id": "3336" }, { "type": "SmallVariant", "id": "3337" }, { "type": "SmallVariant", "id": "3338" }, { "type": "SmallVariant", "id": "3339" }, { "type": "SmallVariant", "id": "3340" }, { "type": "SmallVariant", "id": "3341" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1582/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1582/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "966" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1582/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1582/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1582/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1582/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1126" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1582/?format=api" } }, { "type": "Combination", "id": "OLI1583", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM620040", "OMIM224230", "OMIM613990", "OMIM616353", "OMIM613988", "OMIM615190", "OMIM613989", "OMIM613987", "OMIM305000", "OMIM127550" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2023-05-16T12:03:08.494621" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "1775" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1583/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1583/diseases/?format=api" } }, "variant_set": { "meta": { "count": 7 }, "data": [ { "type": "CopyNumberVariant", "id": "3336" }, { "type": "SmallVariant", "id": "3337" }, { "type": "SmallVariant", "id": "3338" }, { "type": "SmallVariant", "id": "3339" }, { "type": "SmallVariant", "id": "3340" }, { "type": "SmallVariant", "id": "3341" }, { "type": "SmallVariant", "id": "3342" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1583/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1583/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "966" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1583/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1583/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1583/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1583/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1126" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1583/?format=api" } }, { "type": "Combination", "id": "OLI1584", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM620040", "OMIM224230", "OMIM613990", "OMIM616353", "OMIM613988", "OMIM615190", "OMIM613989", "OMIM613987", "OMIM305000", "OMIM127550" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2023-05-16T12:03:08.658228" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "1775" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1584/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1584/diseases/?format=api" } }, "variant_set": { "meta": { "count": 8 }, "data": [ { "type": "CopyNumberVariant", "id": "3336" }, { "type": "SmallVariant", "id": "3337" }, { "type": "SmallVariant", "id": "3343" }, { "type": "SmallVariant", "id": "3344" }, { "type": "SmallVariant", "id": "3339" }, { "type": "SmallVariant", "id": "3340" }, { "type": "SmallVariant", "id": "3341" }, { "type": "SmallVariant", "id": "3345" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1584/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1584/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "966" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1584/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1584/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1584/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1584/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1126" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1584/?format=api" } }, { "type": "Combination", "id": "OLI1586", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM620040", "OMIM224230", "OMIM613990", "OMIM616353", "OMIM613988", "OMIM615190", "OMIM613989", "OMIM613987", "OMIM305000", "OMIM127550" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2023-05-16T12:03:08.970968" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "1775" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1586/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1586/diseases/?format=api" } }, "variant_set": { "meta": { "count": 8 }, "data": [ { "type": "CopyNumberVariant", "id": "3336" }, { "type": "SmallVariant", "id": "3337" }, { "type": "SmallVariant", "id": "3348" }, { "type": "SmallVariant", "id": "3344" }, { "type": "SmallVariant", "id": "3339" }, { "type": "SmallVariant", "id": "3340" }, { "type": "SmallVariant", "id": "3341" }, { "type": "SmallVariant", "id": "3349" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1586/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1586/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "966" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1586/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1586/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1586/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1586/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1126" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1586/?format=api" } }, { "type": "Combination", "id": "OLI1587", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM620040", "OMIM224230", "OMIM613990", "OMIM616353", "OMIM613988", "OMIM615190", "OMIM613989", "OMIM613987", "OMIM305000", "OMIM127550" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2023-05-16T12:03:09.023626" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "1775" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1587/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1587/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3350" }, { "type": "SmallVariant", "id": "3351" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1587/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1587/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "966" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1587/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1587/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1587/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1587/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1126" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1587/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 5 } }