Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1124/genes/?format=api
{ "data": [ { "type": "Gene", "id": "AMH", "attributes": { "go_molecular_function": [ "['growth factor activity', 'hormone activity', 'protein binding', 'type II transforming growth factor beta receptor binding', 'signaling receptor binding']" ], "pathway_id": [ "kegg_path:hsa04024", "kegg_path:hsa04060", "kegg_path:hsa04350", "kegg_path:hsa04390", "R-HSA-1266738", "R-HSA-162582", "R-HSA-201451", "R-HSA-9006936", "R-HSA-9690406" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P03971", "ensembl_id": "None", "entrez_id": "ENSG00000104899", "chromosome_number": "19", "lastmodified": "2021-10-18T11:00:44.744857" }, "relationships": { "variant_set": { "meta": { "count": 11 }, "data": [ { "type": "SmallVariant", "id": "1444" }, { "type": "SmallVariant", "id": "2445" }, { "type": "SmallVariant", "id": "2447" }, { "type": "SmallVariant", "id": "2449" }, { "type": "SmallVariant", "id": "2919" }, { "type": "SmallVariant", "id": "2940" }, { "type": "SmallVariant", "id": "2965" }, { "type": "SmallVariant", "id": "2996" }, { "type": "SmallVariant", "id": "3280" }, { "type": "SmallVariant", "id": "3309" }, { "type": "SmallVariant", "id": "3332" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/AMH/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/AMH/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 11 }, "data": [ { "type": "GeneCombination", "id": "460" }, { "type": "GeneCombination", "id": "824" }, { "type": "GeneCombination", "id": "825" }, { "type": "GeneCombination", "id": "826" }, { "type": "GeneCombination", "id": "968" }, { "type": "GeneCombination", "id": "978" }, { "type": "GeneCombination", "id": "987" }, { "type": "GeneCombination", "id": "1000" }, { "type": "GeneCombination", "id": "1104" }, { "type": "GeneCombination", "id": "1113" }, { "type": "GeneCombination", "id": "1124" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/AMH/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/AMH/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/AMH/?format=api" } }, { "type": "Gene", "id": "FGFR3", "attributes": { "go_molecular_function": [ "['protein tyrosine kinase activity', 'protein serine/threonine/tyrosine kinase activity', 'transmembrane receptor protein tyrosine kinase activity', 'protein binding', 'fibroblast growth factor-activated receptor activity', 'fibroblast growth factor binding', 'identical protein binding', 'ATP binding']" ], "pathway_id": [ "kegg_path:hsa01521", "kegg_path:hsa04010", "kegg_path:hsa04014", "kegg_path:hsa04015", "kegg_path:hsa04020", "kegg_path:hsa04144", "kegg_path:hsa04151", "kegg_path:hsa04550", "kegg_path:hsa04810", "kegg_path:hsa05200", "kegg_path:hsa05206", "kegg_path:hsa05219", "kegg_path:hsa05230", "R-HSA-1226099", "R-HSA-1643685", "R-HSA-1839130", "R-HSA-2033514", "R-HSA-2033515", "R-HSA-5655332", "R-HSA-5663202", "R-HSA-8853334", "R-HSA-8853338", "kegg_path:hsa01521", "kegg_path:hsa04010", "kegg_path:hsa04014", "kegg_path:hsa04015", "kegg_path:hsa04020", "kegg_path:hsa04144", "kegg_path:hsa04151", "kegg_path:hsa04550", "kegg_path:hsa04810", "kegg_path:hsa05200", "kegg_path:hsa05206", "kegg_path:hsa05219", "kegg_path:hsa05230" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P22607", "ensembl_id": "None", "entrez_id": "ENSG00000068078", "chromosome_number": "4", "lastmodified": "2021-10-18T11:00:44.500473" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "1152" }, { "type": "SmallVariant", "id": "3209" }, { "type": "SmallVariant", "id": "3276" }, { "type": "SmallVariant", "id": "3333" }, { "type": "SmallVariant", "id": "3700" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FGFR3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FGFR3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 6 }, "data": [ { "type": "GeneCombination", "id": "369" }, { "type": "GeneCombination", "id": "1072" }, { "type": "GeneCombination", "id": "1082" }, { "type": "GeneCombination", "id": "1102" }, { "type": "GeneCombination", "id": "1124" }, { "type": "GeneCombination", "id": "1252" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FGFR3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FGFR3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/FGFR3/?format=api" } }, { "type": "Gene", "id": "SRA1", "attributes": { "go_molecular_function": [ "['steroid receptor RNA activator RNA binding', 'nuclear receptor coactivator activity', 'transcription coactivator activity', 'DNA binding', 'protein binding']" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "Q9HD15", "ensembl_id": "None", "entrez_id": "ENSG00000213523", "chromosome_number": "5", "lastmodified": "2021-10-18T11:00:44.268998" }, "relationships": { "variant_set": { "meta": { "count": 7 }, "data": [ { "type": "SmallVariant", "id": "35" }, { "type": "SmallVariant", "id": "1211" }, { "type": "SmallVariant", "id": "1424" }, { "type": "SmallVariant", "id": "2777" }, { "type": "SmallVariant", "id": "3299" }, { "type": "SmallVariant", "id": "3301" }, { "type": "SmallVariant", "id": "3305" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SRA1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SRA1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 8 }, "data": [ { "type": "GeneCombination", "id": "14" }, { "type": "GeneCombination", "id": "386" }, { "type": "GeneCombination", "id": "448" }, { "type": "GeneCombination", "id": "928" }, { "type": "GeneCombination", "id": "1109" }, { "type": "GeneCombination", "id": "1110" }, { "type": "GeneCombination", "id": "1112" }, { "type": "GeneCombination", "id": "1124" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SRA1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SRA1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SRA1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }