Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1113/genes/?format=api
{ "data": [ { "type": "Gene", "id": "AMH", "attributes": { "go_molecular_function": [ "['growth factor activity', 'hormone activity', 'protein binding', 'type II transforming growth factor beta receptor binding', 'signaling receptor binding']" ], "pathway_id": [ "kegg_path:hsa04024", "kegg_path:hsa04060", "kegg_path:hsa04350", "kegg_path:hsa04390", "R-HSA-1266738", "R-HSA-162582", "R-HSA-201451", "R-HSA-9006936", "R-HSA-9690406" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P03971", "ensembl_id": "None", "entrez_id": "ENSG00000104899", "chromosome_number": "19", "lastmodified": "2021-10-18T11:00:44.744857" }, "relationships": { "variant_set": { "meta": { "count": 11 }, "data": [ { "type": "SmallVariant", "id": "1444" }, { "type": "SmallVariant", "id": "2445" }, { "type": "SmallVariant", "id": "2447" }, { "type": "SmallVariant", "id": "2449" }, { "type": "SmallVariant", "id": "2919" }, { "type": "SmallVariant", "id": "2940" }, { "type": "SmallVariant", "id": "2965" }, { "type": "SmallVariant", "id": "2996" }, { "type": "SmallVariant", "id": "3280" }, { "type": "SmallVariant", "id": "3309" }, { "type": "SmallVariant", "id": "3332" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/AMH/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/AMH/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 11 }, "data": [ { "type": "GeneCombination", "id": "460" }, { "type": "GeneCombination", "id": "824" }, { "type": "GeneCombination", "id": "825" }, { "type": "GeneCombination", "id": "826" }, { "type": "GeneCombination", "id": "968" }, { "type": "GeneCombination", "id": "978" }, { "type": "GeneCombination", "id": "987" }, { "type": "GeneCombination", "id": "1000" }, { "type": "GeneCombination", "id": "1104" }, { "type": "GeneCombination", "id": "1113" }, { "type": "GeneCombination", "id": "1124" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/AMH/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/AMH/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/AMH/?format=api" } }, { "type": "Gene", "id": "DHX37", "attributes": { "go_molecular_function": [ "['RNA helicase activity', 'protein binding', 'RNA binding', 'ATP hydrolysis activity', 'U3 snoRNA binding', 'ATP binding']" ], "pathway_id": [ "R-HSA-6790901", "R-HSA-6791226", "R-HSA-72312", "R-HSA-8868773", "R-HSA-8953854" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q8IY37", "ensembl_id": "None", "entrez_id": "ENSG00000150990", "chromosome_number": "12", "lastmodified": "2023-05-16T12:02:33.508445" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "3163" }, { "type": "SmallVariant", "id": "3308" }, { "type": "SmallVariant", "id": "3410" }, { "type": "SmallVariant", "id": "3412" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DHX37/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DHX37/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "1056" }, { "type": "GeneCombination", "id": "1058" }, { "type": "GeneCombination", "id": "1113" }, { "type": "GeneCombination", "id": "1144" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DHX37/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DHX37/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/DHX37/?format=api" } }, { "type": "Gene", "id": "MYRF", "attributes": { "go_molecular_function": [ "['DNA-binding transcription factor activity, RNA polymerase II-specific', 'sequence-specific DNA binding', 'DNA-binding transcription factor activity', 'peptidase activity']" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "Q9Y2G1", "ensembl_id": "None", "entrez_id": "ENSG00000124920", "chromosome_number": "11", "lastmodified": "2023-05-16T12:02:33.516815" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "3166" }, { "type": "SmallVariant", "id": "3188" }, { "type": "SmallVariant", "id": "3310" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MYRF/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MYRF/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 5 }, "data": [ { "type": "GeneCombination", "id": "1057" }, { "type": "GeneCombination", "id": "1060" }, { "type": "GeneCombination", "id": "1065" }, { "type": "GeneCombination", "id": "1080" }, { "type": "GeneCombination", "id": "1113" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MYRF/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MYRF/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MYRF/?format=api" } }, { "type": "Gene", "id": "NGLY1", "attributes": { "go_molecular_function": [ "['peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity', 'protein binding', 'metal ion binding']" ], "pathway_id": [ "kegg_path:hsa04141", "R-HSA-392499", "R-HSA-446203", "R-HSA-532668", "R-HSA-597592" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q96IV0", "ensembl_id": "None", "entrez_id": "ENSG00000151092", "chromosome_number": "3", "lastmodified": "2023-05-16T12:02:33.692150" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3307" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NGLY1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NGLY1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1113" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NGLY1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NGLY1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/NGLY1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 4 } }