Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1105/genes/?format=api
{ "data": [ { "type": "Gene", "id": "GPRC6A", "attributes": { "go_molecular_function": [ "['G protein-coupled receptor activity']" ], "pathway_id": [ "kegg_path:hsa04621", "R-HSA-162582", "R-HSA-372790", "R-HSA-388396", "R-HSA-416476", "R-HSA-420499", "R-HSA-500792" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q5T6X5", "ensembl_id": "None", "entrez_id": "ENSG00000173612", "chromosome_number": "6", "lastmodified": "2023-05-16T12:02:33.486621" }, "relationships": { "variant_set": { "meta": { "count": 7 }, "data": [ { "type": "SmallVariant", "id": "3157" }, { "type": "SmallVariant", "id": "3183" }, { "type": "SmallVariant", "id": "3186" }, { "type": "SmallVariant", "id": "3202" }, { "type": "SmallVariant", "id": "3204" }, { "type": "SmallVariant", "id": "3239" }, { "type": "SmallVariant", "id": "3312" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GPRC6A/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GPRC6A/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 11 }, "data": [ { "type": "GeneCombination", "id": "1053" }, { "type": "GeneCombination", "id": "1063" }, { "type": "GeneCombination", "id": "1064" }, { "type": "GeneCombination", "id": "1069" }, { "type": "GeneCombination", "id": "1070" }, { "type": "GeneCombination", "id": "1085" }, { "type": "GeneCombination", "id": "1102" }, { "type": "GeneCombination", "id": "1105" }, { "type": "GeneCombination", "id": "1107" }, { "type": "GeneCombination", "id": "1111" }, { "type": "GeneCombination", "id": "1114" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GPRC6A/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GPRC6A/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/GPRC6A/?format=api" } }, { "type": "Gene", "id": "KAT6B", "attributes": { "go_molecular_function": [ "['transcription coregulator activity', 'DNA binding', 'RNA polymerase II-specific DNA-binding transcription factor binding', 'acetyltransferase activity', 'protein binding', 'metal ion binding', 'histone binding', 'histone acetyltransferase activity']" ], "pathway_id": [ "R-HSA-3214847", "R-HSA-3247509", "R-HSA-4839726" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q8WYB5", "ensembl_id": "None", "entrez_id": "ENSG00000156650", "chromosome_number": "10", "lastmodified": "2023-05-16T12:02:33.654886" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3282" }, { "type": "SmallVariant", "id": "3296" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/KAT6B/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/KAT6B/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "1105" }, { "type": "GeneCombination", "id": "1109" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/KAT6B/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/KAT6B/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/KAT6B/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }