Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1073/genes/?format=api
{ "data": [ { "type": "Gene", "id": "LHX4", "attributes": { "go_molecular_function": [ "['sequence-specific DNA binding', 'DNA-binding transcription activator activity, RNA polymerase II-specific', 'DNA-binding transcription factor activity, RNA polymerase II-specific', 'sequence-specific double-stranded DNA binding', 'methyl-CpG binding', 'protein binding', 'RNA polymerase II transcription regulatory region sequence-specific DNA binding', 'metal ion binding']" ], "pathway_id": [ "R-HSA-1266738", "R-HSA-376176", "R-HSA-422475", "R-HSA-9010553", "R-HSA-9675108" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q969G2", "ensembl_id": "None", "entrez_id": "ENSG00000121454", "chromosome_number": "1", "lastmodified": "2022-08-04T14:14:59.503288" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "2073" }, { "type": "SmallVariant", "id": "2495" }, { "type": "SmallVariant", "id": "2499" }, { "type": "SmallVariant", "id": "3210" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LHX4/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LHX4/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "717" }, { "type": "GeneCombination", "id": "845" }, { "type": "GeneCombination", "id": "847" }, { "type": "GeneCombination", "id": "1073" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LHX4/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LHX4/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/LHX4/?format=api" } }, { "type": "Gene", "id": "PLXNA3", "attributes": { "go_molecular_function": [ "['semaphorin receptor activity', 'protein binding']" ], "pathway_id": [ "kegg_path:hsa04360", "R-HSA-1266738", "R-HSA-373755", "R-HSA-399954", "R-HSA-399955", "R-HSA-399956", "R-HSA-422475", "R-HSA-9675108", "kegg_path:hsa04360", "R-HSA-1266738", "R-HSA-373755", "R-HSA-399954", "R-HSA-399955", "R-HSA-399956", "R-HSA-422475", "R-HSA-9675108" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P51805", "ensembl_id": "None", "entrez_id": "ENSG00000130827", "chromosome_number": "X", "lastmodified": "2023-05-16T12:02:33.541810" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "3176" }, { "type": "SmallVariant", "id": "3211" }, { "type": "SmallVariant", "id": "3217" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PLXNA3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PLXNA3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "1061" }, { "type": "GeneCombination", "id": "1073" }, { "type": "GeneCombination", "id": "1076" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PLXNA3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PLXNA3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PLXNA3/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }