Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1060/genes/?format=api
{ "data": [ { "type": "Gene", "id": "MAP3K1", "attributes": { "go_molecular_function": [ "['protein kinase activity', 'zinc ion binding', 'protein kinase binding', 'protein serine/threonine kinase activity', 'ATP binding', 'MAP kinase kinase kinase activity', 'protein serine kinase activity', 'protein binding', 'protein serine/threonine/tyrosine kinase activity']" ], "pathway_id": [ "kegg_path:hsa04010", "kegg_path:hsa04120", "kegg_path:hsa04530", "kegg_path:hsa04622", "kegg_path:hsa04722", "kegg_path:hsa04912", "kegg_path:hsa04935", "kegg_path:hsa05161", "kegg_path:hsa05166", "R-HSA-166016", "R-HSA-166058", "R-HSA-168138", "R-HSA-168142", "R-HSA-168176", "R-HSA-168179", "R-HSA-168181", "R-HSA-168188", "R-HSA-168249", "R-HSA-168256", "R-HSA-168898", "R-HSA-168928", "R-HSA-181438", "R-HSA-2454202", "R-HSA-2871796", "R-HSA-933542", "R-HSA-975138", "R-HSA-975155", "R-HSA-975871" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q13233", "ensembl_id": "None", "entrez_id": "ENSG00000095015", "chromosome_number": "5", "lastmodified": "2021-10-18T11:00:44.832050" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "1696" }, { "type": "SmallVariant", "id": "2167" }, { "type": "SmallVariant", "id": "3161" }, { "type": "SmallVariant", "id": "3173" }, { "type": "SmallVariant", "id": "3289" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MAP3K1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MAP3K1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 5 }, "data": [ { "type": "GeneCombination", "id": "554" }, { "type": "GeneCombination", "id": "737" }, { "type": "GeneCombination", "id": "1055" }, { "type": "GeneCombination", "id": "1060" }, { "type": "GeneCombination", "id": "1107" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MAP3K1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MAP3K1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MAP3K1/?format=api" } }, { "type": "Gene", "id": "MYRF", "attributes": { "go_molecular_function": [ "['DNA-binding transcription factor activity, RNA polymerase II-specific', 'sequence-specific DNA binding', 'DNA-binding transcription factor activity', 'peptidase activity']" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "Q9Y2G1", "ensembl_id": "None", "entrez_id": "ENSG00000124920", "chromosome_number": "11", "lastmodified": "2023-05-16T12:02:33.516815" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "3166" }, { "type": "SmallVariant", "id": "3188" }, { "type": "SmallVariant", "id": "3310" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MYRF/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MYRF/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 5 }, "data": [ { "type": "GeneCombination", "id": "1057" }, { "type": "GeneCombination", "id": "1060" }, { "type": "GeneCombination", "id": "1065" }, { "type": "GeneCombination", "id": "1080" }, { "type": "GeneCombination", "id": "1113" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MYRF/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MYRF/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MYRF/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }