Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1049/genes/?format=api
{ "data": [ { "type": "Gene", "id": "HOXB3", "attributes": { "go_molecular_function": [ "['DNA-binding transcription factor activity, RNA polymerase II-specific', 'RNA polymerase II cis-regulatory region sequence-specific DNA binding', 'DNA-binding transcription activator activity, RNA polymerase II-specific']" ], "pathway_id": [ "R-HSA-1266738", "R-HSA-5617472", "R-HSA-5619507" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P14651", "ensembl_id": "None", "entrez_id": "ENSG00000120093", "chromosome_number": "17", "lastmodified": "2022-08-04T14:14:59.436573" }, "relationships": { "variant_set": { "meta": { "count": 6 }, "data": [ { "type": "SmallVariant", "id": "2370" }, { "type": "SmallVariant", "id": "2368" }, { "type": "SmallVariant", "id": "2382" }, { "type": "SmallVariant", "id": "3134" }, { "type": "SmallVariant", "id": "3135" }, { "type": "SmallVariant", "id": "3151" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HOXB3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HOXB3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 5 }, "data": [ { "type": "GeneCombination", "id": "802" }, { "type": "GeneCombination", "id": "803" }, { "type": "GeneCombination", "id": "809" }, { "type": "GeneCombination", "id": "1048" }, { "type": "GeneCombination", "id": "1049" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HOXB3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HOXB3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/HOXB3/?format=api" } }, { "type": "Gene", "id": "HOXD3", "attributes": { "go_molecular_function": [ "['RNA polymerase II cis-regulatory region sequence-specific DNA binding', 'DNA-binding transcription activator activity, RNA polymerase II-specific', 'DNA-binding transcription factor activity, RNA polymerase II-specific', 'sequence-specific double-stranded DNA binding', 'protein binding', 'RNA polymerase II transcription regulatory region sequence-specific DNA binding']" ], "pathway_id": [ "R-HSA-1266738", "R-HSA-5617472", "R-HSA-5619507" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "None", "ensembl_id": "None", "entrez_id": "ENSG00000128652", "chromosome_number": "2", "lastmodified": "2023-05-16T12:02:33.438383" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3136" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HOXD3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HOXD3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1049" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HOXD3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HOXD3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/HOXD3/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }