Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1008/genes/?format=api
{ "data": [ { "type": "Gene", "id": "BMP10", "attributes": { "go_molecular_function": [ "['growth factor activity', 'telethonin binding', 'hormone activity', 'protein binding', 'receptor serine/threonine kinase binding', 'cytokine activity']" ], "pathway_id": [ "kegg_path:hsa04060", "R-HSA-1474244", "R-HSA-1566948", "R-HSA-162582", "R-HSA-201451", "R-HSA-2129379", "R-HSA-9006936" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "O95393", "ensembl_id": "None", "entrez_id": "ENSG00000163217", "chromosome_number": "2", "lastmodified": "2023-05-16T12:02:33.202757" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3018" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BMP10/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BMP10/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1008" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BMP10/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BMP10/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/BMP10/?format=api" } }, { "type": "Gene", "id": "SMYD1", "attributes": { "go_molecular_function": [ "['histone-lysine N-methyltransferase activity', 'DNA binding', 'protein binding', 'metal ion binding', 'transcription corepressor activity']" ], "pathway_id": [ "kegg_path:hsa00310", "kegg_path:hsa01100" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q8NB12", "ensembl_id": "None", "entrez_id": "ENSG00000115593", "chromosome_number": "2", "lastmodified": "2023-05-16T12:02:33.199361" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "3017" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SMYD1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SMYD1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "1008" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SMYD1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SMYD1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SMYD1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }