Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/diseases/478/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI036", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 2 }, "omim_id": [ "OMIM614897", "OMIM612702", "OMIM615270", "OMIM147950", "OMIM614840", "OMIM612370", "OMIM308700", "OMIM610628", "OMIM614858", "OMIM614837", "OMIM614838", "OMIM614880", "OMIM615266", "OMIM615267", "OMIM244200", "OMIM615271", "OMIM616030", "OMIM615269", "OMIM618841" ], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:37.935138" }, "relationships": { "diseases": { "meta": { "count": 2 }, "data": [ { "type": "Disease", "id": "478" }, { "type": "Disease", "id": "238666" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI036/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI036/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "77" }, { "type": "SmallVariant", "id": "78" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI036/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI036/variants/?format=api" } }, "reference_set": { "meta": { "count": 2 }, "data": [ { "type": "Reference", "id": "615" }, { "type": "Reference", "id": "667" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI036/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI036/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI036/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI036/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "31" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI036/?format=api" } }, { "type": "Combination", "id": "OLI152", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM614897", "OMIM612702", "OMIM615270", "OMIM147950", "OMIM614840", "OMIM612370", "OMIM308700", "OMIM610628", "OMIM614858", "OMIM614837", "OMIM614838", "OMIM614880", "OMIM615266", "OMIM615267", "OMIM244200", "OMIM615271", "OMIM616030", "OMIM615269", "OMIM618841" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:39.967330" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "478" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI152/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI152/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "78" }, { "type": "SmallVariant", "id": "309" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI152/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI152/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "719" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI152/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI152/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI152/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI152/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "90" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI152/?format=api" } }, { "type": "Combination", "id": "OLI204", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM614897", "OMIM612702", "OMIM615270", "OMIM147950", "OMIM614840", "OMIM612370", "OMIM308700", "OMIM610628", "OMIM614858", "OMIM614837", "OMIM614838", "OMIM614880", "OMIM615266", "OMIM615267", "OMIM244200", "OMIM615271", "OMIM616030", "OMIM615269", "OMIM618841" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:40.834107" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "478" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI204/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI204/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "397" }, { "type": "SmallVariant", "id": "398" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI204/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI204/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "748" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI204/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI204/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI204/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI204/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "31" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI204/?format=api" } }, { "type": "Combination", "id": "OLI205", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM614897", "OMIM612702", "OMIM615270", "OMIM147950", "OMIM614840", "OMIM612370", "OMIM308700", "OMIM610628", "OMIM614858", "OMIM614837", "OMIM614838", "OMIM614880", "OMIM615266", "OMIM615267", "OMIM244200", "OMIM615271", "OMIM616030", "OMIM615269", "OMIM618841" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:40.849660" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "478" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI205/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI205/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "78" }, { "type": "SmallVariant", "id": "309" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI205/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI205/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "748" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI205/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI205/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI205/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI205/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "90" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI205/?format=api" } }, { "type": "Combination", "id": "OLI206", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM614897", "OMIM612702", "OMIM615270", "OMIM147950", "OMIM614840", "OMIM612370", "OMIM308700", "OMIM610628", "OMIM614858", "OMIM614837", "OMIM614838", "OMIM614880", "OMIM615266", "OMIM615267", "OMIM244200", "OMIM615271", "OMIM616030", "OMIM615269", "OMIM618841" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:40.864980" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "478" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI206/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI206/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "78" }, { "type": "SmallVariant", "id": "399" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI206/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI206/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "748" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI206/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI206/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI206/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI206/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "90" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI206/?format=api" } }, { "type": "Combination", "id": "OLI207", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM614897", "OMIM612702", "OMIM615270", "OMIM147950", "OMIM614840", "OMIM612370", "OMIM308700", "OMIM610628", "OMIM614858", "OMIM614837", "OMIM614838", "OMIM614880", "OMIM615266", "OMIM615267", "OMIM244200", "OMIM615271", "OMIM616030", "OMIM615269", "OMIM618841" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:40.879287" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "478" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI207/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI207/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "400" }, { "type": "SmallVariant", "id": "401" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI207/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI207/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "748" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI207/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI207/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI207/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI207/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "116" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI207/?format=api" } }, { "type": "Combination", "id": "OLI208", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 1, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM614897", "OMIM612702", "OMIM615270", "OMIM147950", "OMIM614840", "OMIM612370", "OMIM308700", "OMIM610628", "OMIM614858", "OMIM614837", "OMIM614838", "OMIM614880", "OMIM615266", "OMIM615267", "OMIM244200", "OMIM615271", "OMIM616030", "OMIM615269", "OMIM618841" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:40.894293" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "478" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI208/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI208/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "402" }, { "type": "SmallVariant", "id": "403" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI208/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI208/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "748" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI208/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI208/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI208/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI208/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "136" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI208/?format=api" } }, { "type": "Combination", "id": "OLI287", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 1, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM614897", "OMIM612702", "OMIM615270", "OMIM147950", "OMIM614840", "OMIM612370", "OMIM308700", "OMIM610628", "OMIM614858", "OMIM614837", "OMIM614838", "OMIM614880", "OMIM615266", "OMIM615267", "OMIM244200", "OMIM615271", "OMIM616030", "OMIM615269", "OMIM618841" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:42.225427" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "478" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI287/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI287/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "555" }, { "type": "SmallVariant", "id": "556" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI287/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI287/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "806" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI287/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI287/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI287/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI287/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "190" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI287/?format=api" } }, { "type": "Combination", "id": "OLI288", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM614897", "OMIM612702", "OMIM615270", "OMIM147950", "OMIM614840", "OMIM612370", "OMIM308700", "OMIM610628", "OMIM614858", "OMIM614837", "OMIM614838", "OMIM614880", "OMIM615266", "OMIM615267", "OMIM244200", "OMIM615271", "OMIM616030", "OMIM615269", "OMIM618841" ], "oligogenic_effect": 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