Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/combinations/OLI1164/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "2501", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0008, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0014, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.003, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.000565, "gnomad_AFR_maf": 6.155e-05, "gnomad_AMR_maf": 0.0002024, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.001144, "gnomad_OTH_maf": 0.0004896, "gnomad_SAS_maf": 3.269e-05, "ESP_AA_maf": 0.000227, "ESP_EA_maf": 0.001977 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.634203, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 122649483, "genomic_position_hg38": 120889971, "chromosome": "10", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:55.624105", "ref_allele": "A", "alt_allele": "G", "cdna_change": "c.2305A>G", "protein_change": "p.Met769Val", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1164" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2501/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2501/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2501/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2501/gene/?format=api" }, "data": { "type": "Gene", "id": "WDR11" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2501/?format=api" } }, { "type": "SmallVariant", "id": "2502", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0126, "KGP_genomes_AFR_maf": 0.0446, "KGP_genomes_AMR_maf": 0.0058, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.003911, "gnomad_AFR_maf": 0.04625, "gnomad_AMR_maf": 0.003036, "gnomad_ASJ_maf": 0.004267, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0001387, "gnomad_NFE_maf": 0.0004487, "gnomad_OTH_maf": 0.003911, "gnomad_SAS_maf": 0.000196, "ESP_AA_maf": 0.04222, "ESP_EA_maf": 0.0005814 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.029314, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 5283039, "genomic_position_hg38": 5302393, "chromosome": "20", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:55.630291", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.802C>T", "protein_change": "p.Arg268Cys", "transcript_id": "NM_144773.4", "dbsnp_id": "rs78861628", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1164" }, { "type": "Combination", "id": "OLI1292" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2502/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2502/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2502/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2502/gene/?format=api" }, "data": { "type": "Gene", "id": "PROKR2" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2502/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "Variant serializers": [ "SmallVariantSerializer", "CopyNumberVariantSerializer" ], "size": 2 } }