Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/diseases/406/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI500", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:46.526620" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "406" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI500/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI500/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1063" }, { "type": "SmallVariant", "id": "1064" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI500/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI500/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "788" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI500/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI500/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI500/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI500/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "347" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI500/?format=api" } }, { "type": "Combination", "id": "OLI817", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:52.955028" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "406" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI817/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI817/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1800" }, { "type": "SmallVariant", "id": "1801" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI817/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI817/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "849" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI817/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI817/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI817/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI817/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "347" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI817/?format=api" } }, { "type": "Combination", "id": "OLI818", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:52.971046" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "406" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI818/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI818/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1800" }, { "type": "SmallVariant", "id": "1802" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI818/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI818/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "849" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI818/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI818/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI818/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI818/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "347" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI818/?format=api" } }, { "type": "Combination", "id": "OLI819", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:52.986921" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "406" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI819/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI819/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1801" }, { "type": "SmallVariant", "id": "1803" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI819/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI819/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "849" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI819/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI819/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI819/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI819/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "347" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI819/?format=api" } }, { "type": "Combination", "id": "OLI820", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:53.002759" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "406" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI820/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI820/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1801" }, { "type": "SmallVariant", "id": "1804" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI820/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI820/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "849" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI820/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI820/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI820/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI820/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "347" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI820/?format=api" } }, { "type": "Combination", "id": "OLI821", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:53.018601" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "406" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI821/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI821/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1801" }, { "type": "SmallVariant", "id": "1805" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI821/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI821/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "849" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI821/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI821/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI821/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI821/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "347" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI821/?format=api" } }, { "type": "Combination", "id": "OLI1215", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Dual Molecular Diagnosis", "status": "CU", "effect_predicted": false, "ethnicity": "Japanese", "lastmodified": "2022-08-04T14:15:49.139162" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "406" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1215/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1215/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "2582" }, { "type": "SmallVariant", "id": "2583" }, { "type": "SmallVariant", "id": "2584" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1215/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1215/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "925" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1215/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1215/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1215/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1215/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "860" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1215/?format=api" } }, { "type": "Combination", "id": "OLI1304", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 1, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "European", "lastmodified": "2023-05-16T12:02:46.048877" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "406" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1304/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1304/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "2735" }, { "type": "SmallVariant", "id": "2736" }, { "type": "SmallVariant", "id": "2737" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1304/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1304/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "938" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1304/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1304/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1304/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1304/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "911" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1304/?format=api" } }, { "type": "Combination", "id": "OLI1305", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 1, "final_manual": 1, "final_metascore": 1 }, "omim_id": [], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "European", "lastmodified": "2023-05-16T12:02:46.087248" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "406" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1305/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1305/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2735" }, { "type": "SmallVariant", "id": "2736" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1305/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1305/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "938" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1305/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1305/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1305/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1305/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "912" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1305/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": 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