Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/combinations/OLI1304/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "2735", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0014, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0029, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.002, "KGP_genomes_SAS_maf": 0.0031, "gnomad_maf": 0.003412, "gnomad_AFR_maf": 0.001415, "gnomad_AMR_maf": 0.0006071, "gnomad_ASJ_maf": 0.003472, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.006329, "gnomad_NFE_maf": 0.004334, "gnomad_OTH_maf": 0.003909, "gnomad_SAS_maf": 0.004083, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.519177, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 59404935, "genomic_position_hg38": 58492376, "chromosome": "8", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:56.925737", "ref_allele": "G", "alt_allele": "C", "cdna_change": "c.1192C>G", "protein_change": "p.Pro398Ala", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1304" }, { "type": "Combination", "id": "OLI1305" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2735/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2735/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2735/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2735/gene/?format=api" }, "data": { "type": "Gene", "id": "CYP7A1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2735/?format=api" } }, { "type": "SmallVariant", "id": "2736", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0012, "KGP_genomes_AFR_maf": 0.003, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.001, "KGP_genomes_SAS_maf": 0.001, "gnomad_maf": 0.0007874, "gnomad_AFR_maf": 0.002707, "gnomad_AMR_maf": 0.0005204, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.001055, "gnomad_OTH_maf": 0.001303, "gnomad_SAS_maf": 0.0002613, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.388026, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 12279793, "genomic_position_hg38": 12126859, "chromosome": "12", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:56.931873", "ref_allele": "C", "alt_allele": "A", "cdna_change": "c.4144G>T", "protein_change": "p.Val1382Phe", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1304" }, { "type": "Combination", "id": "OLI1305" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2736/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2736/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2736/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2736/gene/?format=api" }, "data": { "type": "Gene", "id": "LRP6" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2736/?format=api" } }, { "type": "SmallVariant", "id": "2737", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 0.81164, "mutationtaster_prediction": null }, "status": "CU", "genomic_position_hg19": 25889632, "genomic_position_hg38": 25563141, "chromosome": "1", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:56.937920", "ref_allele": "TC", "alt_allele": "CA", "cdna_change": "c.604_605delTCinsCA", "protein_change": "p.Ser202His", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1304" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2737/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2737/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2737/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2737/gene/?format=api" }, "data": { "type": "Gene", "id": "LDLRAP1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2737/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "Variant serializers": [ "SmallVariantSerializer", "CopyNumberVariantSerializer" ], "size": 3 } }