Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/diseases/110/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI039", "attributes": { "scores": { "familial_evidence": 2, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 3, "functional_gene_evidence_manual_harmonized": 3, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 3, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 1, "functional_final_metascore": 2, "final_manual": 2, "final_metascore": 3 }, "omim_id": [ "OMIM615985", "OMIM615992", "OMIM615990", "OMIM615989", "OMIM615991", "OMIM615994", "OMIM615984", "OMIM615995", "OMIM615993", "OMIM600151", "OMIM617119", "OMIM615987", "OMIM605231", "OMIM615982", "OMIM615988", "OMIM615996", "OMIM615981", "OMIM617406", "OMIM615983", "OMIM209900", "OMIM615986" ], "oligogenic_effect": "True Digenic", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:37.993754" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "110" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI039/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI039/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "80" }, { "type": "SmallVariant", "id": "81" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI039/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI039/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "741" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI039/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI039/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI039/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI039/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "32" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI039/?format=api" } }, { "type": "Combination", "id": "OLI041", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM615985", "OMIM615992", "OMIM615990", "OMIM615989", "OMIM615991", "OMIM615994", "OMIM615984", "OMIM615995", "OMIM615993", "OMIM600151", "OMIM617119", "OMIM615987", "OMIM605231", "OMIM615982", "OMIM615988", "OMIM615996", "OMIM615981", "OMIM617406", "OMIM615983", "OMIM209900", "OMIM615986" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:38.028904" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "110" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI041/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI041/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "81" }, { "type": "SmallVariant", "id": "85" }, { "type": "SmallVariant", "id": "86" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI041/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI041/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "741" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI041/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI041/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI041/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI041/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "33" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI041/?format=api" } }, { "type": "Combination", "id": "OLI059", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM615985", "OMIM615992", "OMIM615990", "OMIM615989", "OMIM615991", "OMIM615994", "OMIM615984", "OMIM615995", "OMIM615993", "OMIM600151", "OMIM617119", "OMIM615987", "OMIM605231", "OMIM615982", "OMIM615988", "OMIM615996", "OMIM615981", "OMIM617406", "OMIM615983", "OMIM209900", "OMIM615986" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:38.338820" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "110" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI059/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI059/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "81" }, { "type": "SmallVariant", "id": "117" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI059/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI059/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "741" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI059/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI059/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI059/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI059/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "42" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI059/?format=api" } }, { "type": "Combination", "id": "OLI061", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM615985", "OMIM615992", "OMIM615990", "OMIM615989", "OMIM615991", "OMIM615994", "OMIM615984", "OMIM615995", "OMIM615993", "OMIM600151", "OMIM617119", "OMIM615987", "OMIM605231", "OMIM615982", "OMIM615988", "OMIM615996", "OMIM615981", "OMIM617406", "OMIM615983", "OMIM209900", "OMIM615986" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "South American", "lastmodified": "2021-11-16T17:59:38.372414" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "110" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI061/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI061/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "121" }, { "type": "SmallVariant", "id": "122" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI061/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI061/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "617" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI061/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI061/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI061/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI061/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "43" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI061/?format=api" } }, { "type": "Combination", "id": "OLI062", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM615985", "OMIM615992", "OMIM615990", "OMIM615989", "OMIM615991", "OMIM615994", "OMIM615984", "OMIM615995", "OMIM615993", "OMIM600151", "OMIM617119", "OMIM615987", "OMIM605231", "OMIM615982", "OMIM615988", "OMIM615996", "OMIM615981", "OMIM617406", "OMIM615983", "OMIM209900", "OMIM615986" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:38.387839" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "110" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI062/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI062/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "80" }, { "type": "SmallVariant", "id": "123" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI062/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI062/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "617" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI062/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI062/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI062/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI062/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "44" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI062/?format=api" } }, { "type": "Combination", "id": "OLI063", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM615985", "OMIM615992", "OMIM615990", "OMIM615989", "OMIM615991", "OMIM615994", "OMIM615984", "OMIM615995", "OMIM615993", "OMIM600151", "OMIM617119", "OMIM615987", "OMIM605231", "OMIM615982", "OMIM615988", "OMIM615996", "OMIM615981", "OMIM617406", "OMIM615983", "OMIM209900", "OMIM615986" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:38.407046" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "110" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI063/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI063/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "80" }, { "type": "SmallVariant", "id": "124" }, { "type": "SmallVariant", "id": "125" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI063/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI063/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "617" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI063/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI063/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI063/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI063/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "45" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI063/?format=api" } }, { "type": "Combination", "id": "OLI064", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM615985", "OMIM615992", "OMIM615990", "OMIM615989", "OMIM615991", "OMIM615994", "OMIM615984", "OMIM615995", "OMIM615993", "OMIM600151", "OMIM617119", "OMIM615987", "OMIM605231", "OMIM615982", "OMIM615988", "OMIM615996", "OMIM615981", "OMIM617406", "OMIM615983", "OMIM209900", "OMIM615986" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:38.427090" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "110" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI064/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI064/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "80" }, { "type": "SmallVariant", "id": "126" }, { "type": "SmallVariant", "id": "127" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI064/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI064/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "617" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI064/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI064/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI064/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI064/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "46" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI064/?format=api" } }, { "type": "Combination", "id": "OLI065", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM615985", "OMIM615992", "OMIM615990", "OMIM615989", "OMIM615991", "OMIM615994", "OMIM615984", "OMIM615995", "OMIM615993", "OMIM600151", "OMIM617119", "OMIM615987", "OMIM605231", "OMIM615982", "OMIM615988", "OMIM615996", "OMIM615981", "OMIM617406", "OMIM615983", "OMIM209900", "OMIM615986" ], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:38.442620" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "110" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI065/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI065/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "80" }, { "type": "SmallVariant", "id": "128" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI065/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI065/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "617" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI065/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI065/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI065/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI065/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "46" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI065/?format=api" } }, { "type": "Combination", "id": "OLI066", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM615985", "OMIM615992", "OMIM615990", 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