Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/combinations/OLI549/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "366",
            "attributes": {
                "gene_relationship": [
                    "Directly interacting",
                    "Same protein complex",
                    "Involved in the same disease",
                    "Affecting the same tissue",
                    "Relevant pathways for phenotype",
                    "Same pathway"
                ],
                "protein_interactions": [
                    "(KCNE1, KCNH2)",
                    "(KCNE1, KCNQ1)"
                ],
                "common_pathways": [
                    "Muscle contraction",
                    "Voltage gated Potassium channels",
                    "Phase 3 - rapid repolarisation",
                    "Neuronal System",
                    "Phase 2 - plateau phase",
                    "Cardiac conduction",
                    "Adrenergic signaling in cardiomyocytes"
                ],
                "genecomb_metascore": 2,
                "lastmodified": "2021-10-18T11:01:04.769938"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI549"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/366/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/366/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 3
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "KCNE1"
                        },
                        {
                            "type": "Gene",
                            "id": "KCNH2"
                        },
                        {
                            "type": "Gene",
                            "id": "KCNQ1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/366/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/366/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/366/?format=api"
            }
        }
    ]
}