Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/combinations/OLI1240/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "873",
            "attributes": {
                "gene_relationship": [
                    "Relevant pathways for phenotype",
                    "Same protein complex",
                    "Co-expression",
                    "Same pathway"
                ],
                "protein_interactions": [
                    "(MCM2, MCM4)"
                ],
                "common_pathways": [
                    "Cell Cycle",
                    "Cell cycle",
                    "Mitotic",
                    "Synthesis of DNA",
                    "Activation of ATR in response to replication stress",
                    "DNA replication",
                    "Unwinding of DNA",
                    "Orc1 removal from chromatin",
                    "Activation of the pre-replicative complex",
                    "Mitotic G1 phase and G1/S transition",
                    "Cell Cycle Checkpoints",
                    "DNA Replication Pre-Initiation",
                    "G2/M Checkpoints",
                    "S Phase",
                    "Assembly of the pre-replicative complex",
                    "G1/S Transition",
                    "DNA Replication",
                    "Switching of origins to a post-replicative state",
                    "DNA strand elongation"
                ],
                "genecomb_metascore": 2,
                "lastmodified": "2024-03-01T14:27:38.866112"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1240"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/873/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/873/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "MCM2"
                        },
                        {
                            "type": "Gene",
                            "id": "MCM4"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/873/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/873/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/873/?format=api"
            }
        }
    ]
}