Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/761/gene/?format=api
{ "data": { "type": "Gene", "id": "PTPN11", "attributes": { "go_molecular_function": [ "phosphoprotein phosphatase activity", "non-membrane spanning protein tyrosine phosphatase activity", "protein tyrosine phosphatase activity", "hydrolase activity" ], "pathway_id": [ "R-HSA-1170546", "R-HSA-2404192", "R-HSA-9702518", "R-HSA-2219528", "R-HSA-180292", "R-HSA-5654695", "R-HSA-5654712", "R-HSA-109704", "R-HSA-2586552", "R-HSA-5654700", "R-HSA-449147", "R-HSA-373752", "kegg_path:hsa04670", "R-HSA-9645135", "R-HSA-1257604", "kegg_path:hsa04650", "R-HSA-9006925", "kegg_path:hsa05130", "R-HSA-913531", "R-HSA-114604", "R-HSA-177929", "R-HSA-391160", "kegg_path:hsa04014", "R-HSA-5683057", "R-HSA-2428928", "kegg_path:hsa04722", "kegg_path:hsa05120", "R-HSA-1059683", "R-HSA-186763", "kegg_path:hsa04360", "R-HSA-1643685", "R-HSA-1280218", "R-HSA-5654741", "R-HSA-446652", "R-HSA-877312", "R-HSA-6806834", "R-HSA-1280215", "R-HSA-76002", "kegg_path:hsa04625", "R-HSA-418886", "R-HSA-9682385", "R-HSA-186797", "R-HSA-5654736", "R-HSA-1295596", "R-HSA-5654716", "R-HSA-74160", "R-HSA-74752", "R-HSA-166166", "R-HSA-202733", "R-HSA-5684996", "R-HSA-936964", "kegg_path:hsa04630", "R-HSA-74751", "R-HSA-912694", "R-HSA-112411", "R-HSA-8854691", "R-HSA-909733", "R-HSA-418346", "R-HSA-9703648", "R-HSA-432142", "kegg_path:hsa05205", "R-HSA-168898", "R-HSA-5654733", "R-HSA-877300", "R-HSA-1433557", "R-HSA-5654732", "R-HSA-9006115", "R-HSA-8878171", "R-HSA-168256", "R-HSA-5654706", "R-HSA-6783589", "R-HSA-73857", "R-HSA-9008059", "kegg_path:hsa04072", "R-HSA-512988", "R-HSA-5654727", "R-HSA-166016", "R-HSA-5654720", "R-HSA-5654687", "R-HSA-9607240", "R-HSA-1500931", "R-HSA-5654710", "kegg_path:hsa04920", "R-HSA-110056", "kegg_path:hsa05168", "R-HSA-210990", "R-HSA-5654738", "R-HSA-5654743", "R-HSA-9028731", "R-HSA-9675108", "R-HSA-210993", "R-HSA-422475", "R-HSA-212436", "R-HSA-6811558", "R-HSA-2219530", "R-HSA-168249", "R-HSA-2428924", "kegg_path:hsa05211", "kegg_path:hsa04931", "R-HSA-388841", "R-HSA-389948", "R-HSA-5654693", "R-HSA-9006934", "R-HSA-937061", "kegg_path:hsa05220", "R-HSA-190236", "R-HSA-199418", "R-HSA-5654708", "kegg_path:hsa05235", "R-HSA-109582", "R-HSA-8934593", "R-HSA-112409", "R-HSA-5654726", "R-HSA-5663202", "R-HSA-162582", "R-HSA-8853659", "R-HSA-166520", "R-HSA-1266738", "R-HSA-389513", "R-HSA-5654689", "R-HSA-5654696", "R-HSA-112399", "R-HSA-8865999" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "Q06124", "ensembl_id": "ENSG00000179295", "entrez_id": "5781", "chromosome_number": "12" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "761" }, { "type": "SmallVariant", "id": "1186" }, { "type": "SmallVariant", "id": "1308" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PTPN11/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PTPN11/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "240" }, { "type": "GeneCombination", "id": "380" }, { "type": "GeneCombination", "id": "410" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PTPN11/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PTPN11/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PTPN11/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.381685", "status": "CU", "curator": null, "submitter": "cnachteg" } }