Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/679/gene/?format=api
{ "data": { "type": "Gene", "id": "ITPR1", "attributes": { "go_molecular_function": [ "phosphatidylinositol binding", "inositol 1,4,5 trisphosphate binding", "protein binding", "calcium ion binding", "calcium-release channel activity", "inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity" ], "pathway_id": [ "kegg_path:hsa04621", "R-HSA-983705", "R-HSA-195721", "kegg_path:hsa04723", "R-HSA-372790", "R-HSA-9006925", "R-HSA-3858494", "R-HSA-418457", "R-HSA-2871809", "R-HSA-5578775", "kegg_path:hsa04921", "R-HSA-163685", "kegg_path:hsa04912", "kegg_path:hsa04210", "kegg_path:hsa04611", "kegg_path:hsa04726", "kegg_path:hsa04020", "R-HSA-162582", "kegg_path:hsa04925", "kegg_path:hsa05022", "R-HSA-9664323", "R-HSA-983695", "kegg_path:hsa05131", "kegg_path:hsa04724", "R-HSA-2029485", "R-HSA-9658195", "kegg_path:hsa04218", "kegg_path:hsa05205", "R-HSA-139853", "R-HSA-418594", "R-HSA-5663205", "kegg_path:hsa04371", "kegg_path:hsa04725", "kegg_path:hsa04728", "R-HSA-392154", "R-HSA-418346", "kegg_path:hsa04922", "kegg_path:hsa04928", "kegg_path:hsa05163", "R-HSA-5576891", "R-HSA-9664433", "R-HSA-416476", "R-HSA-112040", "R-HSA-112043", "kegg_path:hsa04972", "R-HSA-381676", "kegg_path:hsa04927", "R-HSA-1489509", "R-HSA-418360", "R-HSA-422356", "R-HSA-1280218", "R-HSA-168249", "R-HSA-5621481", "kegg_path:hsa04935", "kegg_path:hsa04270", "kegg_path:hsa04713", "kegg_path:hsa04970", "R-HSA-1643685", "R-HSA-109582", "kegg_path:hsa04114", "kegg_path:hsa04625", "kegg_path:hsa04730", "kegg_path:hsa04720", "kegg_path:hsa05167", "R-HSA-5607763", "R-HSA-9006934", "R-HSA-76002", "kegg_path:hsa04750", "kegg_path:hsa05016", "R-HSA-2454202", "kegg_path:hsa05017", "R-HSA-9662851", "kegg_path:hsa04924", "kegg_path:hsa04022", "R-HSA-194138", "R-HSA-4086398", "R-HSA-114508", "kegg_path:hsa04934", "R-HSA-111885", "R-HSA-168256", "kegg_path:hsa04140", "kegg_path:hsa04929", "R-HSA-388396", "R-HSA-5607764", "R-HSA-397014", "kegg_path:hsa04918", "kegg_path:hsa04971", "R-HSA-2029480", "kegg_path:hsa05170", "R-HSA-1430728", "kegg_path:hsa05012", "kegg_path:hsa04070", "kegg_path:hsa05010", "kegg_path:hsa05020", "kegg_path:hsa04540", "kegg_path:hsa04915", "R-HSA-4420097", "R-HSA-5218921" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "Q14643", "ensembl_id": "ENSG00000150995", "entrez_id": "3708", "chromosome_number": "3" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "670" }, { "type": "SmallVariant", "id": "679" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ITPR1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ITPR1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "219" }, { "type": "GeneCombination", "id": "220" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ITPR1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ITPR1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ITPR1/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.563079", "status": "CU", "curator": null, "submitter": "cnachteg" } }