Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/variants/3732/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI1761", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 2 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:35.308690" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "93665" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1761/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1761/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3731" }, { "type": "SmallVariant", "id": "3732" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1761/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1761/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "999" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1761/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1761/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1761/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1761/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1258" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1761/?format=api" } }, { "type": "Combination", "id": "OLI1762", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:35.370061" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "93665" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1762/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1762/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "3714" }, { "type": "SmallVariant", "id": "3725" }, { "type": "SmallVariant", "id": "3732" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1762/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1762/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "999" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1762/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1762/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1762/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1762/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1258" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1762/?format=api" } }, { "type": "Combination", "id": "OLI1763", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:35.426826" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "93665" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1763/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1763/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3714" }, { "type": "SmallVariant", "id": "3732" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1763/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1763/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "999" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1763/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1763/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1763/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1763/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1258" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1763/?format=api" } }, { "type": "Combination", "id": "OLI1766", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 2 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:35.608799" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "93665" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1766/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1766/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "3735" }, { "type": "SmallVariant", "id": "3732" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1766/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1766/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "999" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1766/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1766/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1766/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1766/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1258" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1766/?format=api" } }, { "type": "Combination", "id": "OLI1767", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:35.664492" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "93665" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1767/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1767/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "3714" }, { "type": "SmallVariant", "id": "3716" }, { "type": "SmallVariant", "id": "3732" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1767/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1767/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "999" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1767/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1767/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1767/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1767/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1258" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1767/?format=api" } }, { "type": "Combination", "id": "OLI1779", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:36.544923" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "93665" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1779/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1779/diseases/?format=api" } }, "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "3725" }, { "type": "SmallVariant", "id": "3726" }, { "type": "SmallVariant", "id": "3737" }, { "type": "SmallVariant", "id": "3732" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1779/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1779/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "999" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1779/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1779/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1779/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1779/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1263" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1779/?format=api" } }, { "type": "Combination", "id": "OLI1780", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:36.637666" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "93665" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1780/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1780/diseases/?format=api" } }, "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "3714" }, { "type": "SmallVariant", "id": "3725" }, { "type": "SmallVariant", "id": "3744" }, { "type": "SmallVariant", "id": "3732" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1780/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1780/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "999" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1780/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1780/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1780/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1780/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1263" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1780/?format=api" } }, { "type": "Combination", "id": "OLI1781", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:36.700445" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "93665" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1781/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1781/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "3714" }, { "type": "SmallVariant", "id": "3717" }, { "type": "SmallVariant", "id": "3732" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1781/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1781/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "999" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1781/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1781/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1781/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1781/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1264" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1781/?format=api" } }, { "type": "Combination", "id": "OLI1785", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2024-02-29T15:02:36.961526" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "93665" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1785/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1785/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "3714" }, { "type": "SmallVariant", "id": "3732" }, { "type": "SmallVariant", "id": "3739" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1785/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1785/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "999" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1785/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1785/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1785/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1785/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "1265" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1785/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 9 } }