Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/3465/gene/?format=api
{ "data": { "type": "Gene", "id": "COL4A3", "attributes": { "go_molecular_function": [ "['integrin binding', 'metalloendopeptidase inhibitor activity', 'extracellular matrix structural constituent conferring tensile strength', 'protein binding', 'structural molecule activity', 'extracellular matrix structural constituent']" ], "pathway_id": [ "kegg_path:hsa04151", "kegg_path:hsa04510", "kegg_path:hsa04512", "kegg_path:hsa04926", "kegg_path:hsa04933", "kegg_path:hsa04974", "kegg_path:hsa05146", "kegg_path:hsa05165", "kegg_path:hsa05200", "kegg_path:hsa05222", "R-HSA-1266738", "R-HSA-1442490", "R-HSA-1474228", "R-HSA-1474244", "R-HSA-1474290", "R-HSA-162582", "R-HSA-1650814", "R-HSA-186797", "R-HSA-2022090", "R-HSA-216083", "R-HSA-2214320", "R-HSA-2243919", "R-HSA-3000157", "R-HSA-3000171", "R-HSA-3000178", "R-HSA-375165", "R-HSA-419037", "R-HSA-422475", "R-HSA-8948216", "R-HSA-9006934", "R-HSA-9675108" ], "essential_gene": "Non-essential", "status": null, "uniprot_acc": "Q01955", "ensembl_id": "None", "entrez_id": "ENSG00000169031", "chromosome_number": "2" }, "relationships": { "variant_set": { "meta": { "count": 24 }, "data": [ { "type": "CopyNumberVariant", "id": "834" }, { "type": "SmallVariant", "id": "73" }, { "type": "SmallVariant", "id": "278" }, { "type": "SmallVariant", "id": "312" }, { "type": "SmallVariant", "id": "316" }, { "type": "SmallVariant", "id": "617" }, { "type": "SmallVariant", "id": "618" }, { "type": "SmallVariant", "id": "822" }, { "type": "SmallVariant", "id": "824" }, { "type": "SmallVariant", "id": "826" }, { "type": "SmallVariant", "id": "828" }, { "type": "SmallVariant", "id": "830" }, { "type": "SmallVariant", "id": "832" }, { "type": "SmallVariant", "id": "1094" }, { "type": "SmallVariant", "id": "2105" }, { "type": "SmallVariant", "id": "2107" }, { "type": "SmallVariant", "id": "2109" }, { "type": "SmallVariant", "id": "2111" }, { "type": "SmallVariant", "id": "2640" }, { "type": "SmallVariant", "id": "2881" }, { "type": "SmallVariant", "id": "3458" }, { "type": "SmallVariant", "id": "3462" }, { "type": "SmallVariant", "id": "3465" }, { "type": "SmallVariant", "id": "3520" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/COL4A3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/COL4A3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "29" }, { "type": "GeneCombination", "id": "99" }, { "type": "GeneCombination", "id": "210" }, { "type": "GeneCombination", "id": "1186" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/COL4A3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/COL4A3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/COL4A3/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.722330", "status": "CU", "curator": null, "submitter": "cnachteg" } }