Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/2816/gene/?format=api
{ "data": { "type": "Gene", "id": "STAT1", "attributes": { "go_molecular_function": [ "['tumor necrosis factor receptor binding', 'protein phosphatase 2A binding', 'DNA-binding transcription factor activity, RNA polymerase II-specific', 'double-stranded DNA binding', 'protein binding', 'histone binding', 'identical protein binding', 'DNA-binding transcription factor activity', 'transcription coactivator binding', 'ubiquitin-like protein ligase binding', 'nuclear receptor binding', 'RNA polymerase II transcription regulatory region sequence-specific DNA binding', 'histone acetyltransferase binding', 'cadherin binding', 'RNA polymerase II core promoter sequence-specific DNA binding', 'protein homodimerization activity', 'RNA polymerase II cis-regulatory region sequence-specific DNA binding', 'enzyme binding', 'CCR5 chemokine receptor binding', 'transcription corepressor binding', 'promoter-specific chromatin binding']" ], "pathway_id": [ "kegg_path:hsa04062", "kegg_path:hsa04217", "kegg_path:hsa04380", "kegg_path:hsa04620", "kegg_path:hsa04621", "kegg_path:hsa04625", "kegg_path:hsa04630", "kegg_path:hsa04658", "kegg_path:hsa04659", "kegg_path:hsa04917", "kegg_path:hsa04919", "kegg_path:hsa04933", "kegg_path:hsa04935", "kegg_path:hsa05140", "kegg_path:hsa05145", "kegg_path:hsa05152", "kegg_path:hsa05160", "kegg_path:hsa05161", "kegg_path:hsa05162", "kegg_path:hsa05164", "kegg_path:hsa05165", "kegg_path:hsa05167", "kegg_path:hsa05168", "kegg_path:hsa05169", "kegg_path:hsa05171", "kegg_path:hsa05200", "kegg_path:hsa05212", "kegg_path:hsa05235", "kegg_path:hsa05321", "R-HSA-1059683", "R-HSA-1169408", "R-HSA-1169410", "R-HSA-1226099", "R-HSA-1280215", "R-HSA-1433557", "R-HSA-157118", "R-HSA-162582", "R-HSA-1643685", "R-HSA-168256", "R-HSA-1839117", "R-HSA-1839124", "R-HSA-186763", "R-HSA-186797", "R-HSA-212436", "R-HSA-447115", "R-HSA-449147", "R-HSA-451927", "R-HSA-5655302", "R-HSA-5663202", "R-HSA-6783589", "R-HSA-6785807", "R-HSA-73857", "R-HSA-74160", "R-HSA-8854691", "R-HSA-8878166", "R-HSA-8939902", "R-HSA-8984722", "R-HSA-8985947", "R-HSA-9006934", "R-HSA-9012852", "R-HSA-9013508", "R-HSA-9020956", "R-HSA-9020958", "R-HSA-913531", "R-HSA-9669938", "R-HSA-9670439", "R-HSA-9671555", "R-HSA-9673767", "R-HSA-9673770", "R-HSA-982772" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "P42224", "ensembl_id": "None", "entrez_id": "ENSG00000115415", "chromosome_number": "2" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2808" }, { "type": "SmallVariant", "id": "2816" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/STAT1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/STAT1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "937" }, { "type": "GeneCombination", "id": "938" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/STAT1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/STAT1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/STAT1/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2023-05-16T12:02:32.946501", "status": "CU", "curator": null, "submitter": "cnachteg" } }