Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/2498/gene/?format=api
{ "data": { "type": "Gene", "id": "HS6ST1", "attributes": { "go_molecular_function": [ "['heparan sulfate 6-O-sulfotransferase activity', 'protein binding', 'sulfotransferase activity']" ], "pathway_id": [ "kegg_path:hsa00534", "R-HSA-1430728", "R-HSA-1630316", "R-HSA-1638091", "R-HSA-2022928", "R-HSA-71387" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "O60243", "ensembl_id": "None", "entrez_id": "ENSG00000136720", "chromosome_number": "2" }, "relationships": { "variant_set": { "meta": { "count": 10 }, "data": [ { "type": "SmallVariant", "id": "783" }, { "type": "SmallVariant", "id": "807" }, { "type": "SmallVariant", "id": "853" }, { "type": "SmallVariant", "id": "1415" }, { "type": "SmallVariant", "id": "2498" }, { "type": "SmallVariant", "id": "2670" }, { "type": "SmallVariant", "id": "2779" }, { "type": "SmallVariant", "id": "2839" }, { "type": "SmallVariant", "id": "2969" }, { "type": "SmallVariant", "id": "3267" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HS6ST1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HS6ST1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 10 }, "data": [ { "type": "GeneCombination", "id": "245" }, { "type": "GeneCombination", "id": "252" }, { "type": "GeneCombination", "id": "444" }, { "type": "GeneCombination", "id": "847" }, { "type": "GeneCombination", "id": "889" }, { "type": "GeneCombination", "id": "929" }, { "type": "GeneCombination", "id": "944" }, { "type": "GeneCombination", "id": "263" }, { "type": "GeneCombination", "id": "989" }, { "type": "GeneCombination", "id": "1098" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HS6ST1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HS6ST1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/HS6ST1/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.274137", "status": "CU", "curator": null, "submitter": "cnachteg" } }