Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/2381/gene/?format=api
{ "data": { "type": "Gene", "id": "GNAS", "attributes": { "go_molecular_function": [ "['G-protein beta/gamma-subunit complex binding', 'adenylate cyclase activator activity', 'D1 dopamine receptor binding', 'GTP binding', 'insulin-like growth factor receptor binding', 'corticotropin-releasing hormone receptor 1 binding', 'mu-type opioid receptor binding', 'G protein-coupled receptor binding', 'protein binding', 'metal ion binding', 'ionotropic glutamate receptor binding', 'GTPase activity', 'beta-2 adrenergic receptor binding']" ], "pathway_id": [ "kegg_path:hsa01522", "kegg_path:hsa04015", "kegg_path:hsa04020", "kegg_path:hsa04024", "kegg_path:hsa04072", "kegg_path:hsa04261", "kegg_path:hsa04270", "kegg_path:hsa04540", "kegg_path:hsa04611", "kegg_path:hsa04713", "kegg_path:hsa04714", "kegg_path:hsa04724", "kegg_path:hsa04726", "kegg_path:hsa04728", "kegg_path:hsa04730", "kegg_path:hsa04750", "kegg_path:hsa04911", "kegg_path:hsa04912", "kegg_path:hsa04913", "kegg_path:hsa04915", "kegg_path:hsa04916", "kegg_path:hsa04918", "kegg_path:hsa04921", "kegg_path:hsa04922", "kegg_path:hsa04923", "kegg_path:hsa04924", "kegg_path:hsa04925", "kegg_path:hsa04926", "kegg_path:hsa04927", "kegg_path:hsa04928", "kegg_path:hsa04934", "kegg_path:hsa04935", "kegg_path:hsa04961", "kegg_path:hsa04962", "kegg_path:hsa04970", "kegg_path:hsa04971", "kegg_path:hsa04972", "kegg_path:hsa04976", "kegg_path:hsa05012", "kegg_path:hsa05030", "kegg_path:hsa05031", "kegg_path:hsa05032", "kegg_path:hsa05034", "kegg_path:hsa05110", "kegg_path:hsa05142", "kegg_path:hsa05146", "kegg_path:hsa05163", "kegg_path:hsa05165", "kegg_path:hsa05200", "kegg_path:hsa05414", "kegg_path:hsa01522", "kegg_path:hsa04015", "kegg_path:hsa04020", "kegg_path:hsa04024", "kegg_path:hsa04072", "kegg_path:hsa04261", "kegg_path:hsa04270", "kegg_path:hsa04540", "kegg_path:hsa04611", "kegg_path:hsa04713", "kegg_path:hsa04714", "kegg_path:hsa04724", "kegg_path:hsa04726", "kegg_path:hsa04728", "kegg_path:hsa04730", "kegg_path:hsa04750", "kegg_path:hsa04911", "kegg_path:hsa04912", "kegg_path:hsa04913", "kegg_path:hsa04915", "kegg_path:hsa04916", "kegg_path:hsa04918", "kegg_path:hsa04921", "kegg_path:hsa04922", "kegg_path:hsa04923", "kegg_path:hsa04924", "kegg_path:hsa04925", "kegg_path:hsa04926", "kegg_path:hsa04927", "kegg_path:hsa04928", "kegg_path:hsa04934", "kegg_path:hsa04935", "kegg_path:hsa04961", "kegg_path:hsa04962", "kegg_path:hsa04970", "kegg_path:hsa04971", "kegg_path:hsa04972", "kegg_path:hsa04976", "kegg_path:hsa05012", "kegg_path:hsa05030", "kegg_path:hsa05031", "kegg_path:hsa05032", "kegg_path:hsa05034", "kegg_path:hsa05110", "kegg_path:hsa05142", "kegg_path:hsa05146", "kegg_path:hsa05163", "kegg_path:hsa05165", "kegg_path:hsa05200", "kegg_path:hsa05414", "kegg_path:hsa01522", "kegg_path:hsa04015", "kegg_path:hsa04020", "kegg_path:hsa04024", "kegg_path:hsa04072", "kegg_path:hsa04261", "kegg_path:hsa04270", "kegg_path:hsa04540", "kegg_path:hsa04611", "kegg_path:hsa04713", "kegg_path:hsa04714", "kegg_path:hsa04724", "kegg_path:hsa04726", "kegg_path:hsa04728", "kegg_path:hsa04730", "kegg_path:hsa04750", "kegg_path:hsa04911", "kegg_path:hsa04912", "kegg_path:hsa04913", "kegg_path:hsa04915", "kegg_path:hsa04916", "kegg_path:hsa04918", "kegg_path:hsa04921", "kegg_path:hsa04922", "kegg_path:hsa04923", "kegg_path:hsa04924", "kegg_path:hsa04925", "kegg_path:hsa04926", "kegg_path:hsa04927", "kegg_path:hsa04928", "kegg_path:hsa04934", "kegg_path:hsa04935", "kegg_path:hsa04961", "kegg_path:hsa04962", "kegg_path:hsa04970", "kegg_path:hsa04971", "kegg_path:hsa04972", "kegg_path:hsa04976", "kegg_path:hsa05012", "kegg_path:hsa05030", "kegg_path:hsa05031", "kegg_path:hsa05032", "kegg_path:hsa05034", "kegg_path:hsa05110", "kegg_path:hsa05142", "kegg_path:hsa05146", "kegg_path:hsa05163", "kegg_path:hsa05165", "kegg_path:hsa05200", "kegg_path:hsa05414", "R-HSA-109582", "R-HSA-1430728", "R-HSA-162582", "R-HSA-163359", "R-HSA-163685", "R-HSA-1643685", "R-HSA-164378", "R-HSA-372790", "R-HSA-373080", "R-HSA-381676", "R-HSA-382551", "R-HSA-388396", "R-HSA-392851", "R-HSA-418346", "R-HSA-418555", "R-HSA-418594", "R-HSA-418597", "R-HSA-420092", "R-HSA-422356", "R-HSA-432040", "R-HSA-445717", "R-HSA-500792", "R-HSA-5358351", "R-HSA-5610787", "R-HSA-5663205", "R-HSA-9658195", "R-HSA-9660821", "R-HSA-9662851", "R-HSA-9664433", "R-HSA-109582", "R-HSA-1430728", "R-HSA-162582", "R-HSA-163359", "R-HSA-163685", "R-HSA-1643685", "R-HSA-164378", "R-HSA-372790", "R-HSA-373080", "R-HSA-381676", "R-HSA-382551", "R-HSA-388396", "R-HSA-392851", "R-HSA-418346", "R-HSA-418555", "R-HSA-418594", "R-HSA-418597", "R-HSA-420092", "R-HSA-422356", "R-HSA-432040", "R-HSA-445717", "R-HSA-500792", "R-HSA-5358351", "R-HSA-5610787", "R-HSA-5663205", "R-HSA-9658195", "R-HSA-9660821", "R-HSA-9662851", "R-HSA-9664433" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "Q5JWF2", "ensembl_id": "None", "entrez_id": "ENSG00000087460", "chromosome_number": "20" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2381" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GNAS/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GNAS/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "808" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GNAS/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GNAS/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/GNAS/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2022-08-04T14:14:58.936352", "status": "CU", "curator": null, "submitter": "cnachteg" } }