Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/237/gene/?format=api
{ "data": { "type": "Gene", "id": "PSMB8", "attributes": { "go_molecular_function": [ "peptidase activity", "hydrolase activity", "threonine-type endopeptidase activity", "endopeptidase activity" ], "pathway_id": [ "R-HSA-2467813", "R-HSA-5387390", "R-HSA-176409", "R-HSA-109581", "R-HSA-2454202", "R-HSA-174143", "R-HSA-351202", "R-HSA-5668541", "R-HSA-212436", "R-HSA-9675108", "R-HSA-422475", "R-HSA-5658442", "R-HSA-5607764", "R-HSA-168256", "R-HSA-180585", "R-HSA-73857", "R-HSA-9010553", "R-HSA-5663202", "R-HSA-5678895", "R-HSA-69052", "R-HSA-8953897", "R-HSA-5357801", "R-HSA-1266738", "R-HSA-179419", "R-HSA-1234174", "R-HSA-5621481", "R-HSA-5632684", "R-HSA-69541", "R-HSA-75815", "R-HSA-4641257", "R-HSA-983168", "R-HSA-382556", "R-HSA-5676590", "R-HSA-8854050", "R-HSA-5689603", "R-HSA-69563", "R-HSA-8941858", "R-HSA-450408", "R-HSA-5610785", "R-HSA-174084", "R-HSA-449147", "R-HSA-8878159", "R-HSA-69206", "R-HSA-8939902", "R-HSA-9006925", "R-HSA-180534", "R-HSA-349425", "R-HSA-913531", "R-HSA-8951664", "R-HSA-5362768", "R-HSA-376176", "R-HSA-8852276", "R-HSA-1236974", "R-HSA-69239", "R-HSA-174184", "R-HSA-5688426", "R-HSA-5619115", "R-HSA-5358346", "R-HSA-74160", "R-HSA-8953854", "R-HSA-5684996", "R-HSA-1236978", "R-HSA-5610787", "R-HSA-5610783", "R-HSA-68949", "R-HSA-453276", "R-HSA-68882", "R-HSA-201681", "R-HSA-69202", "R-HSA-1280215", "R-HSA-450531", "R-HSA-453274", "R-HSA-176408", "R-HSA-202424", "R-HSA-597592", "R-HSA-8948751", "R-HSA-5619084", "R-HSA-983169", "R-HSA-1640170", "R-HSA-169911", "R-HSA-392499", "R-HSA-162906", "R-HSA-69656", "R-HSA-202403", "R-HSA-68867", "R-HSA-8878171", "R-HSA-1430728", "R-HSA-69580", "R-HSA-71291", "R-HSA-2262752", "R-HSA-5607761", "R-HSA-9604323", "R-HSA-162582", "R-HSA-5687128", "R-HSA-69306", "R-HSA-5663205", "R-HSA-9013694", "R-HSA-174113", "R-HSA-211733", "R-HSA-4641258", "R-HSA-168249", "R-HSA-187577", "R-HSA-350562", "R-HSA-69017", "R-HSA-69610", "R-HSA-174154", "R-HSA-382551", "R-HSA-9020702", "R-HSA-4086400", "R-HSA-176814", "R-HSA-8939236", "R-HSA-5673001", "kegg_path:hsa03050", "R-HSA-983705", "R-HSA-1257604", "R-HSA-195721", "R-HSA-3858494", "R-HSA-5683057", "R-HSA-6807070", "R-HSA-4608870", "R-HSA-174178", "R-HSA-68886", "R-HSA-1168372", "R-HSA-69278", "R-HSA-69601", "R-HSA-2555396", "R-HSA-69242", "R-HSA-69613", "R-HSA-69620", "R-HSA-68827", "R-HSA-8878166", "R-HSA-1234176", "R-HSA-5610780", "R-HSA-69002", "R-HSA-2871837", "R-HSA-5689880", "R-HSA-69481", "R-HSA-909733", "R-HSA-69275", "R-HSA-1280218", "R-HSA-1643685", "R-HSA-453279", "R-HSA-195253", "R-HSA-446652", "R-HSA-69615", "R-HSA-5358351", "R-HSA-162909", "R-HSA-157118", "R-HSA-1169091", "R-HSA-1236975" ], "essential_gene": "Non-essential", "status": null, "uniprot_acc": "P28062", "ensembl_id": "ENSG00000204264", "entrez_id": "5696", "chromosome_number": "6" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "237" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PSMB8/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PSMB8/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "87" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PSMB8/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PSMB8/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PSMB8/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.702399", "status": "CU", "curator": null, "submitter": "cnachteg" } }