Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/2304/gene/?format=api
{ "data": { "type": "Gene", "id": "ATR", "attributes": { "go_molecular_function": [ "MutSalpha complex binding", "protein binding", "protein serine/threonine kinase activity", "DNA binding", "MutLalpha complex binding", "protein serine/threonine/tyrosine kinase activity", "protein kinase activity", "ATP binding", "protein serine kinase activity" ], "pathway_id": [ "R-HSA-3371556", "R-HSA-6783310", "kegg_path:hsa03460", "R-HSA-5685938", "R-HSA-5693532", "R-HSA-6796648", "R-HSA-1500620", "R-HSA-5693616", "R-HSA-8953897", "R-HSA-5633007", "kegg_path:hsa05165", "kegg_path:hsa05166", "R-HSA-5693607", "kegg_path:hsa04115", "R-HSA-69481", "R-HSA-1640170", "R-HSA-3371453", "kegg_path:hsa04218", "R-HSA-212436", "R-HSA-3700989", "R-HSA-5685942", "R-HSA-1474165", "kegg_path:hsa04110", "R-HSA-69473", "R-HSA-73894", "R-HSA-5693579", "R-HSA-6804756", "R-HSA-1221632", "R-HSA-176187", "kegg_path:hsa05170", "R-HSA-5693538", "R-HSA-73857", "R-HSA-5693567", "R-HSA-69620", "R-HSA-2262752", "R-HSA-74160" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "Q13535", "ensembl_id": "ENSG00000175054", "entrez_id": "545", "chromosome_number": "3" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2251" }, { "type": "SmallVariant", "id": "2304" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ATR/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ATR/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "759" }, { "type": "GeneCombination", "id": "773" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ATR/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ATR/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ATR/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2022-08-04T14:14:57.634607", "status": "CU", "curator": null, "submitter": "cnachteg" } }