Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/2293/gene/?format=api
{ "data": { "type": "Gene", "id": "RIPK1", "attributes": { "go_molecular_function": [ "protein homodimerization activity", "death domain binding", "protein binding", "JUN kinase kinase kinase activity", "death receptor binding", "identical protein binding", "protein serine/threonine kinase activity", "protein serine/threonine/tyrosine kinase activity", "ubiquitin protein ligase binding", "protein kinase activity", "ATP binding", "protein serine kinase activity", "protein-containing complex binding" ], "pathway_id": [ "kegg_path:hsa04620", "R-HSA-933543", "R-HSA-140534", "R-HSA-5357769", "kegg_path:hsa05170", "R-HSA-9645723", "kegg_path:hsa05169", "R-HSA-1643685", "R-HSA-1810476", "R-HSA-2562578", "R-HSA-75893", "R-HSA-168898", "R-HSA-5663205", "kegg_path:hsa05132", "kegg_path:hsa04623", "kegg_path:hsa04622", "R-HSA-5689880", "kegg_path:hsa05160", "kegg_path:hsa05163", "R-HSA-9693928", "kegg_path:hsa05130", "R-HSA-162582", "R-HSA-166166", "R-HSA-5357801", "R-HSA-983712", "kegg_path:hsa04621", "R-HSA-3295583", "R-HSA-5357905", "kegg_path:hsa05131", "R-HSA-166016", "R-HSA-168164", "R-HSA-1834949", "R-HSA-73887", "kegg_path:hsa04620", "kegg_path:hsa04668", "kegg_path:hsa04210", "kegg_path:hsa05170", "R-HSA-168928", "R-HSA-69416", "R-HSA-5218859", "R-HSA-5688426", "R-HSA-937041", "kegg_path:hsa04217", "R-HSA-168256", "R-HSA-5218900", "R-HSA-9679191", "R-HSA-9679506", "kegg_path:hsa05169", "R-HSA-392499", "kegg_path:hsa04064", "kegg_path:hsa04623", "R-HSA-3371378", "kegg_path:hsa05132", "kegg_path:hsa05160", "kegg_path:hsa05163", "kegg_path:hsa04622", "R-HSA-5689896", "R-HSA-9686347", "kegg_path:hsa04621", "kegg_path:hsa05130", "R-HSA-109581", "R-HSA-5357786", "kegg_path:hsa05131", "R-HSA-1606322", "R-HSA-5213460", "R-HSA-597592", "R-HSA-9013957", "kegg_path:hsa04668", "R-HSA-382551", "kegg_path:hsa04210", "R-HSA-168927", "R-HSA-5357956", "R-HSA-937061", "R-HSA-2672351", "kegg_path:hsa04217", "kegg_path:hsa04064", "R-HSA-168249", "R-HSA-5675482" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "Q13546", "ensembl_id": "ENSG00000137275", "entrez_id": "8737", "chromosome_number": "6" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2293" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/RIPK1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/RIPK1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "769" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/RIPK1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/RIPK1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/RIPK1/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2022-08-04T14:14:58.852981", "status": "CU", "curator": null, "submitter": "cnachteg" } }