Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/2003/gene/?format=api
{ "data": { "type": "Gene", "id": "EZH2", "attributes": { "go_molecular_function": [ "chromatin DNA binding", "protein binding", "histone methyltransferase activity (H3-K27 specific)", "primary miRNA binding", "transcription corepressor activity", "histone-lysine N-methyltransferase activity", "RNA polymerase II core promoter sequence-specific DNA binding", "histone methyltransferase activity", "promoter-specific chromatin binding", "chromatin binding", "protein-lysine N-methyltransferase activity", "transcription corepressor binding", "ribonucleoprotein complex binding", "RNA polymerase II cis-regulatory region sequence-specific DNA binding" ], "pathway_id": [ "R-HSA-73857", "kegg_path:hsa01100", "kegg_path:hsa05206", "R-HSA-1643685", "R-HSA-5619507", "R-HSA-162582", "R-HSA-2559583", "R-HSA-8943724", "R-HSA-9006925", "R-HSA-9609646", "R-HSA-1257604", "R-HSA-8953897", "R-HSA-4839726", "R-HSA-5617472", "R-HSA-1266738", "R-HSA-212300", "R-HSA-212165", "R-HSA-2559580", "kegg_path:hsa00310", "R-HSA-3247509", "R-HSA-6807070", "R-HSA-8953750", "R-HSA-212436", "R-HSA-3214841", "R-HSA-5663205", "R-HSA-9609690", "R-HSA-2262752", "R-HSA-74160" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "Q15910", "ensembl_id": "ENSG00000106462", "entrez_id": "2146", "chromosome_number": "7" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2003" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/EZH2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/EZH2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "690" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/EZH2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/EZH2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/EZH2/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2022-08-04T14:14:57.818231", "status": "CU", "curator": null, "submitter": "cnachteg" } }