Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/1088/gene/?format=api
{ "data": { "type": "Gene", "id": "CDK4", "attributes": { "go_molecular_function": [ "transferase activity", "kinase activity", "ATP binding", "nucleotide binding", "protein serine/threonine kinase activity", "cyclin-dependent protein serine/threonine kinase activity" ], "pathway_id": [ "kegg_path:hsa05222", "kegg_path:hsa05203", "R-HSA-2559580", "kegg_path:hsa04115", "kegg_path:hsa05162", "kegg_path:hsa05223", "kegg_path:hsa05160", "R-HSA-912446", "R-HSA-69206", "kegg_path:hsa04151", "kegg_path:hsa05212", "R-HSA-69231", "R-HSA-69242", "R-HSA-9006927", "kegg_path:hsa05164", "kegg_path:hsa05218", "R-HSA-9630794", "kegg_path:hsa05225", "kegg_path:hsa04530", "R-HSA-69278", "kegg_path:hsa04660", "kegg_path:hsa05160", "kegg_path:hsa04218", "kegg_path:hsa05165", "kegg_path:hsa05200", "R-HSA-2262752", "R-HSA-9632697", "R-HSA-9632700", "R-HSA-9675126", "kegg_path:hsa05222", "kegg_path:hsa04934", "kegg_path:hsa05214", "R-HSA-8878166", "R-HSA-9630750", "R-HSA-9687139", "kegg_path:hsa05203", "R-HSA-74160", "kegg_path:hsa04115", "kegg_path:hsa05162", "R-HSA-162582", "R-HSA-8849470", "R-HSA-9630791", "R-HSA-1500620", "R-HSA-2559582", "R-HSA-4839726", "R-HSA-69236", "kegg_path:hsa05223", "R-HSA-8953897", "R-HSA-9632693", "kegg_path:hsa05225", "kegg_path:hsa05220", "R-HSA-69202", "kegg_path:hsa04933", "kegg_path:hsa05167", "R-HSA-9661069", "kegg_path:hsa04530", "R-HSA-3214858", "kegg_path:hsa04660", "R-HSA-8848021", "kegg_path:hsa05212", "kegg_path:hsa04151", "kegg_path:hsa05169", "R-HSA-1643685", "R-HSA-453279", "kegg_path:hsa04110", "R-HSA-187577", "kegg_path:hsa05224", "R-HSA-2559585", "R-HSA-75815", "kegg_path:hsa05218", "kegg_path:hsa05164", "R-HSA-9630747", "kegg_path:hsa05200", "kegg_path:hsa05165", "kegg_path:hsa04934", "kegg_path:hsa05214", "R-HSA-1640170", "R-HSA-212436", "kegg_path:hsa05166", "kegg_path:hsa05163", "kegg_path:hsa05219", "R-HSA-9675132", "R-HSA-9659787", "kegg_path:hsa04218", "kegg_path:hsa01522", "kegg_path:hsa05169", "R-HSA-73857", "kegg_path:hsa04110", "kegg_path:hsa05224", "R-HSA-1474165", "kegg_path:hsa04933", "kegg_path:hsa05167", "R-HSA-381340", "kegg_path:hsa05220", "R-HSA-2559583", "R-HSA-69656", "kegg_path:hsa05219", "kegg_path:hsa05163", "R-HSA-1266738", "kegg_path:hsa05166", "R-HSA-3247509", "R-HSA-9616222", "kegg_path:hsa01522" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "P11802", "ensembl_id": "ENSG00000135446", "entrez_id": "1019", "chromosome_number": "12" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1088" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CDK4/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CDK4/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "356" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CDK4/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CDK4/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CDK4/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2026 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.645062", "status": "CU", "curator": null, "submitter": "cnachteg" } }