Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/references/815/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI648", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 1, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM614897", "OMIM612702", "OMIM615270", "OMIM147950", "OMIM614840", "OMIM612370", "OMIM308700", "OMIM610628", "OMIM614858", "OMIM614837", "OMIM614838", "OMIM614880", "OMIM615266", "OMIM615267", "OMIM244200", "OMIM615271", "OMIM616030", "OMIM615269", "OMIM618841" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:49.617553" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "478" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI648/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI648/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "397" }, { "type": "SmallVariant", "id": "1409" }, { "type": "SmallVariant", "id": "1410" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI648/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI648/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "815" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI648/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI648/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI648/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI648/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "442" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI648/?format=api" } }, { "type": "Combination", "id": "OLI649", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM614897", "OMIM612702", "OMIM615270", "OMIM147950", "OMIM614840", "OMIM612370", "OMIM308700", "OMIM610628", "OMIM614858", "OMIM614837", "OMIM614838", "OMIM614880", "OMIM615266", "OMIM615267", "OMIM244200", "OMIM615271", "OMIM616030", "OMIM615269", "OMIM618841" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:49.637651" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "478" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI649/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI649/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "1411" }, { "type": "SmallVariant", "id": "1412" }, { "type": "SmallVariant", "id": "1413" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI649/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI649/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "815" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI649/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI649/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI649/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI649/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "443" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI649/?format=api" } }, { "type": "Combination", "id": "OLI650", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 1, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:49.653561" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "174590" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI650/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI650/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1414" }, { "type": "SmallVariant", "id": "1415" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI650/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI650/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "815" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI650/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI650/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI650/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI650/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "444" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI650/?format=api" } }, { "type": "Combination", "id": "OLI651", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:49.675415" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "174590" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI651/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI651/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "1414" }, { "type": "SmallVariant", "id": "1416" }, { "type": "SmallVariant", "id": "1417" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI651/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI651/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "815" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI651/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI651/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI651/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI651/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "445" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI651/?format=api" } }, { "type": "Combination", "id": "OLI652", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 1, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:49.696818" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "174590" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI652/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI652/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "1418" }, { "type": "SmallVariant", "id": "1419" }, { "type": "SmallVariant", "id": "1420" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI652/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI652/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "815" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI652/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI652/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI652/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI652/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "446" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI652/?format=api" } }, { "type": "Combination", "id": "OLI653", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:49.712029" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "174590" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI653/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI653/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1421" }, { "type": "SmallVariant", "id": "1422" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI653/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI653/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "815" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI653/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI653/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI653/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI653/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "447" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI653/?format=api" } }, { "type": "Combination", "id": "OLI654", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:49.727972" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "174590" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI654/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI654/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1423" }, { "type": "SmallVariant", "id": "1424" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI654/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI654/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "815" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI654/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI654/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI654/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI654/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "448" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI654/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 7 } }