Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/references/717/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI231", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 1, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:41.282327" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "217569" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI231/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI231/diseases/?format=api" } }, "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "447" }, { "type": "SmallVariant", "id": "448" }, { "type": "SmallVariant", "id": "449" }, { "type": "SmallVariant", "id": "450" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI231/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI231/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "717" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI231/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI231/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI231/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI231/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "148" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI231/?format=api" } }, { "type": "Combination", "id": "OLI232", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 1, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM180849", "OMIM601494", "OMIM617760", "OMIM613426", "OMIM615373", "OMIM613684", "OMIM613424", "OMIM604169", "OMIM255310", "OMIM609470", "OMIM601493", "OMIM610543", "OMIM615092", "OMIM300580", "OMIM615396", "OMIM611878" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:41.304406" }, "relationships": { "diseases": { "meta": { "count": 2 }, "data": [ { "type": "Disease", "id": "54260" }, { "type": "Disease", "id": "783" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI232/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI232/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "451" }, { "type": "SmallVariant", "id": "452" }, { "type": "SmallVariant", "id": "453" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI232/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI232/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "717" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI232/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI232/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI232/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI232/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "149" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI232/?format=api" } }, { "type": "Combination", "id": "OLI233", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 1, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:41.320325" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "217569" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI233/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI233/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "454" }, { "type": "SmallVariant", "id": "455" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI233/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI233/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "717" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI233/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI233/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI233/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI233/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "150" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI233/?format=api" } }, { "type": "Combination", "id": "OLI234", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:41.335683" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "217569" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI234/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI234/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "456" }, { "type": "SmallVariant", "id": "457" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI234/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI234/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "717" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI234/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI234/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI234/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI234/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "151" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI234/?format=api" } }, { "type": "Combination", "id": "OLI235", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:41.351013" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "217604" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI235/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI235/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "458" }, { "type": "SmallVariant", "id": "459" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI235/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI235/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "717" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI235/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI235/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI235/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI235/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "152" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI235/?format=api" } }, { "type": "Combination", "id": "OLI236", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 1, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:41.370673" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "217604" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI236/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI236/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "452" }, { "type": "SmallVariant", "id": "453" }, { "type": "SmallVariant", "id": "460" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI236/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI236/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "717" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI236/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI236/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI236/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI236/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "150" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI236/?format=api" } }, { "type": "Combination", "id": "OLI237", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 0, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 0, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2021-11-16T17:59:41.390008" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "217569" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI237/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI237/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "461" }, { "type": "SmallVariant", "id": "462" }, { "type": "SmallVariant", "id": "463" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI237/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI237/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "717" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI237/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI237/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI237/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI237/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "153" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI237/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2024 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 7 } }