Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/references/655/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI195", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 2, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 2, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 1 }, "omim_id": [ "OMIM125851", "OMIM616329", "OMIM614880", "OMIM610628", "OMIM612702", "OMIM614840", "OMIM615269", "OMIM615270", "OMIM308700", "OMIM244200", "OMIM614841", "OMIM613370", "OMIM146110", "OMIM614858", "OMIM613375", "OMIM615266", "OMIM606392", "OMIM600496", "OMIM606391", "OMIM147950", "OMIM610508", "OMIM614839", "OMIM614837", "OMIM616511", "OMIM125850", "OMIM612225", "OMIM612370", "OMIM614842", "OMIM609812", "OMIM606394", "OMIM614838" ], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:40.685642" }, "relationships": { "diseases": { "meta": { "count": 2 }, "data": [ { "type": "Disease", "id": "432" }, { "type": "Disease", "id": "238666" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI195/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI195/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "379" }, { "type": "SmallVariant", "id": "380" }, { "type": "SmallVariant", "id": "381" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI195/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI195/variants/?format=api" } }, "reference_set": { "meta": { "count": 3 }, "data": [ { "type": "Reference", "id": "655" }, { "type": "Reference", "id": "667" }, { "type": "Reference", "id": "780" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI195/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI195/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI195/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI195/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "130" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI195/?format=api" } }, { "type": "Combination", "id": "OLI197", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 3, "functional_gene_evidence_manual_harmonized": 3, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 3, "functional_variant_evidence_manual": 2, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 2, "functional_final_manual": 3, "functional_final_metascore": 3, "final_manual": 2, "final_metascore": 2 }, "omim_id": [ "OMIM125851", "OMIM616329", "OMIM614880", "OMIM610628", "OMIM612702", "OMIM614840", "OMIM615269", "OMIM615270", "OMIM308700", "OMIM244200", "OMIM614841", "OMIM613370", "OMIM146110", "OMIM614858", "OMIM613375", "OMIM615266", "OMIM606392", "OMIM600496", "OMIM606391", "OMIM147950", "OMIM610508", "OMIM614839", "OMIM614837", "OMIM616511", "OMIM125850", "OMIM612225", "OMIM612370", "OMIM614842", "OMIM609812", "OMIM606394", "OMIM614838" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:40.717528" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "432" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI197/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI197/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "384" }, { "type": "SmallVariant", "id": "385" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI197/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI197/variants/?format=api" } }, "reference_set": { "meta": { "count": 3 }, "data": [ { "type": "Reference", "id": "655" }, { "type": "Reference", "id": "780" }, { "type": "Reference", "id": "848" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI197/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI197/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI197/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI197/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "131" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI197/?format=api" } }, { "type": "Combination", "id": "OLI198", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 2, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 2, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 1 }, "omim_id": [ "OMIM125851", "OMIM616329", "OMIM614880", "OMIM610628", "OMIM612702", "OMIM614840", "OMIM615269", "OMIM615270", "OMIM308700", "OMIM244200", "OMIM614841", "OMIM613370", "OMIM146110", "OMIM614858", "OMIM613375", "OMIM615266", "OMIM606392", "OMIM600496", "OMIM606391", "OMIM147950", "OMIM610508", "OMIM614839", "OMIM614837", "OMIM616511", "OMIM125850", "OMIM612225", "OMIM612370", "OMIM614842", "OMIM609812", "OMIM606394", "OMIM614838" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:40.732995" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "432" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI198/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI198/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "386" }, { "type": "SmallVariant", "id": "387" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI198/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI198/variants/?format=api" } }, "reference_set": { "meta": { "count": 2 }, "data": [ { "type": "Reference", "id": "655" }, { "type": "Reference", "id": "780" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI198/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI198/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI198/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI198/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "130" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI198/?format=api" } }, { "type": "Combination", "id": "OLI199", "attributes": { "scores": { "familial_evidence": 3, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 2, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 2, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 3, "final_metascore": 3 }, "omim_id": [ "OMIM125851", "OMIM616329", "OMIM614880", "OMIM610628", "OMIM612702", "OMIM614840", "OMIM615269", "OMIM615270", "OMIM308700", "OMIM244200", "OMIM614841", "OMIM613370", "OMIM146110", "OMIM614858", "OMIM613375", "OMIM615266", "OMIM606392", "OMIM600496", "OMIM606391", "OMIM147950", "OMIM610508", "OMIM614839", "OMIM614837", "OMIM616511", "OMIM125850", "OMIM612225", "OMIM612370", "OMIM614842", "OMIM609812", "OMIM606394", "OMIM614838" ], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:40.754917" }, "relationships": { "diseases": { "meta": { "count": 2 }, "data": [ { "type": "Disease", "id": "432" }, { "type": "Disease", "id": "238666" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI199/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI199/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "381" }, { "type": "SmallVariant", "id": "387" }, { "type": "SmallVariant", "id": "388" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI199/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI199/variants/?format=api" } }, "reference_set": { "meta": { "count": 5 }, "data": [ { "type": "Reference", "id": "655" }, { "type": "Reference", "id": "661" }, { "type": "Reference", "id": "667" }, { "type": "Reference", "id": "780" }, { "type": "Reference", "id": "848" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI199/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI199/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI199/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI199/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "130" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI199/?format=api" } }, { "type": "Combination", "id": "OLI365", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 1 }, "omim_id": [ "OMIM614880", "OMIM610628", "OMIM618841", "OMIM612702", "OMIM614840", "OMIM615269", "OMIM615270", "OMIM308700", "OMIM244200", "OMIM614858", "OMIM615266", "OMIM615267", "OMIM614897", "OMIM616030", "OMIM615271", "OMIM147950", "OMIM614837", "OMIM612370", "OMIM614838" ], "oligogenic_effect": "Monogenic+Modifier", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:44.199017" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "478" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI365/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI365/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "800" }, { "type": "SmallVariant", "id": "801" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI365/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI365/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "655" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI365/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI365/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI365/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI365/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "244" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI365/?format=api" } }, { "type": "Combination", "id": "OLI366", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM614880", "OMIM610628", "OMIM618841", "OMIM612702", "OMIM614840", "OMIM615269", "OMIM615270", "OMIM308700", "OMIM244200", "OMIM614858", "OMIM615266", "OMIM615267", "OMIM614897", "OMIM616030", "OMIM615271", "OMIM147950", "OMIM614837", "OMIM612370", "OMIM614838" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:44.215023" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "478" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI366/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI366/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "802" }, { "type": "SmallVariant", "id": "803" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI366/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI366/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "655" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI366/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI366/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI366/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI366/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "251" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI366/?format=api" } }, { "type": "Combination", "id": "OLI367", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 1 }, "omim_id": [ "OMIM614880", "OMIM610628", "OMIM618841", "OMIM612702", "OMIM614840", "OMIM615269", "OMIM615270", "OMIM308700", "OMIM244200", "OMIM614858", "OMIM615266", "OMIM615267", "OMIM614897", "OMIM616030", "OMIM615271", "OMIM147950", "OMIM614837", "OMIM612370", "OMIM614838" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:44.248520" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "478" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI367/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI367/diseases/?format=api" } }, "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "384" }, { "type": "SmallVariant", "id": "804" }, { "type": "SmallVariant", "id": "805" }, { "type": "SmallVariant", "id": "806" }, { "type": "SmallVariant", "id": "807" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI367/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI367/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "655" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI367/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI367/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI367/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI367/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "252" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI367/?format=api" } }, { "type": "Combination", "id": "OLI368", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 1 }, "omim_id": [ "OMIM614880", "OMIM610628", "OMIM618841", "OMIM612702", "OMIM614840", "OMIM615269", "OMIM615270", "OMIM308700", "OMIM244200", "OMIM614858", "OMIM615266", "OMIM615267", "OMIM614897", "OMIM616030", "OMIM615271", "OMIM147950", "OMIM614837", "OMIM612370", "OMIM614838" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-16T17:59:44.264791" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "478" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI368/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI368/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "808" }, { "type": "SmallVariant", "id": "809" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI368/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI368/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "655" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI368/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI368/references/?format=api" } }, "gene_combination": { "links": { "self": 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