Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/ZFPM2/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "862", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0008, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.004, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.0004945, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.006693, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 8.88e-06, "gnomad_OTH_maf": 0.0003312, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.205808, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 106814417, "genomic_position_hg38": 105802189, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:45.666141", "ref_allele": "A", "alt_allele": "C", "cdna_change": "c.2107A>C", "protein_change": "p.Met703Leu", "transcript_id": "NM_012082.3", "dbsnp_id": "rs121908603", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI400" }, { "type": "Combination", "id": "OLI927" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/862/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/862/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/862/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/862/gene/?format=api" }, "data": { "type": "Gene", "id": "ZFPM2" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/862/?format=api" } }, { "type": "SmallVariant", "id": "1213", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 5.244e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 4.65e-05, "gnomad_NFE_maf": 9.81e-05, "gnomad_OTH_maf": 0.0001665, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0002434 }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 3.715424, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 106573591, "genomic_position_hg38": 105561363, "chromosome": "8", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:47.813015", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.302G>A", "protein_change": "p.Gly101Glu", "transcript_id": "NM_012082.3", "dbsnp_id": "rs199605561", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI574" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1213/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1213/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1213/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1213/gene/?format=api" }, "data": { "type": "Gene", "id": "ZFPM2" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1213/?format=api" } }, { "type": "SmallVariant", "id": "1446", "attributes": { "frequencies": { "KGP_genomes_maf": 0.001, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0014, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.004, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.003376, "gnomad_AFR_maf": 0.0005204, "gnomad_AMR_maf": 0.00281, "gnomad_ASJ_maf": 0.003483, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.005445, "gnomad_NFE_maf": 0.004869, "gnomad_OTH_maf": 0.002976, "gnomad_SAS_maf": 0.0005555, "ESP_AA_maf": 0.0002593, "ESP_EA_maf": 0.004977 }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.247745, "mutationtaster_prediction": null }, "status": "CU", "genomic_position_hg19": 106813942, "genomic_position_hg38": 105801714, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:49.199326", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.1632G>A", "protein_change": "p.Met544Ile", "transcript_id": "NM_012082.3", "dbsnp_id": "rs187043152", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI669" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1446/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1446/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1446/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1446/gene/?format=api" }, "data": { "type": "Gene", "id": "ZFPM2" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1446/?format=api" } }, { "type": "SmallVariant", "id": "3216", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0002, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.001, "gnomad_maf": 3.304e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 2.968e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 9.127e-06, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0002022, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.066125, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 106814844, "genomic_position_hg38": 105802616, "chromosome": "8", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:59.774948", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.2534C>T", "protein_change": "p.Thr845Met", "transcript_id": "NM_012082", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1531" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/3216/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/3216/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/3216/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/3216/gene/?format=api" }, "data": { "type": "Gene", "id": "ZFPM2" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/3216/?format=api" } }, { "type": "SmallVariant", "id": "3250", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 1.606e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 3.543e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.195972, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 106815365, "genomic_position_hg38": 105803137, "chromosome": "8", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:59.988509", "ref_allele": "G", "alt_allele": "T", "cdna_change": "c.3055G>T", "protein_change": "p.Ala1019Ser", "transcript_id": "NM_012082", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1546" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/3250/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/3250/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/3250/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/3250/gene/?format=api" }, "data": { "type": "Gene", "id": "ZFPM2" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/3250/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "Variant serializers": [ "SmallVariantSerializer", "CopyNumberVariantSerializer" ], "size": 5 } }