Gene Instance
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genes/VEGFA/?format=api
{ "data": { "type": "Gene", "id": "VEGFA", "attributes": { "go_molecular_function": [ "['vascular endothelial growth factor receptor 2 binding', 'extracellular matrix binding', 'fibronectin binding', 'protein homodimerization activity', 'growth factor activity', 'vascular endothelial growth factor receptor 1 binding', 'vascular endothelial growth factor receptor binding', 'protein binding', 'platelet-derived growth factor receptor binding', 'heparin binding', 'receptor ligand activity', 'chemoattractant activity', 'identical protein binding', 'cytokine activity']" ], "pathway_id": [ "kegg_path:hsa01521", "kegg_path:hsa04010", "kegg_path:hsa04014", "kegg_path:hsa04015", "kegg_path:hsa04020", "kegg_path:hsa04066", "kegg_path:hsa04151", "kegg_path:hsa04370", "kegg_path:hsa04510", "kegg_path:hsa04926", "kegg_path:hsa04933", "kegg_path:hsa05163", "kegg_path:hsa05165", "kegg_path:hsa05167", "kegg_path:hsa05200", "kegg_path:hsa05205", "kegg_path:hsa05206", "kegg_path:hsa05211", "kegg_path:hsa05212", "kegg_path:hsa05219", "kegg_path:hsa05323", "kegg_path:hsa05418", "R-HSA-109582", "R-HSA-114608", "R-HSA-1234158", "R-HSA-1234174", "R-HSA-1280215", "R-HSA-162582", "R-HSA-168256", "R-HSA-194138", "R-HSA-194313", "R-HSA-195399", "R-HSA-212436", "R-HSA-2262752", "R-HSA-449147", "R-HSA-6785807", "R-HSA-73857", "R-HSA-74160", "R-HSA-76002", "R-HSA-76005", "R-HSA-8864260", "R-HSA-8866910", "R-HSA-8953897", "R-HSA-9006934" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "J3KPA4", "ensembl_id": "None", "entrez_id": "ENSG00000112715", "chromosome_number": "6" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2623" }, { "type": "SmallVariant", "id": "3354" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/VEGFA/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/VEGFA/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "871" }, { "type": "GeneCombination", "id": "1128" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/VEGFA/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/VEGFA/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/VEGFA/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2023-05-16T12:02:32.427835", "status": "CU", "curator": null, "submitter": "cnachteg" } }