Gene Instance
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genes/VCP/?format=api
{ "data": { "type": "Gene", "id": "VCP", "attributes": { "go_molecular_function": [ "protein phosphatase binding", "ADP binding", "K48-linked polyubiquitin modification-dependent protein binding", "protein domain specific binding", "protein binding", "ATP hydrolysis activity", "deubiquitinase activator activity", "identical protein binding", "polyubiquitin modification-dependent protein binding", "ubiquitin-like protein ligase binding", "ubiquitin protein ligase binding", "lipid binding", "ubiquitin-specific protease binding", "ATP binding", "RNA binding", "MHC class I protein binding", "BAT3 complex binding" ], "pathway_id": [ "R-HSA-446203", "kegg_path:hsa04141", "R-HSA-9612973", "R-HSA-73893", "R-HSA-5663205", "R-HSA-1632852", "kegg_path:hsa05022", "R-HSA-110320", "R-HSA-5358346", "R-HSA-5663202", "R-HSA-2262752", "R-HSA-5678895", "R-HSA-8953897", "R-HSA-162582", "R-HSA-9678110", "R-HSA-5689877", "R-HSA-382551", "R-HSA-5688426", "R-HSA-9694614", "R-HSA-5619115", "R-HSA-9694516", "R-HSA-168249", "R-HSA-392499", "R-HSA-5362768", "R-HSA-8852135", "R-HSA-9679506", "R-HSA-532668", "R-HSA-1643685", "R-HSA-168256", "R-HSA-8866654", "R-HSA-8876725", "R-HSA-9678108", "R-HSA-382556", "R-HSA-5358351", "R-HSA-73894", "R-HSA-9646399", "kegg_path:hsa05134", "R-HSA-110313", "R-HSA-5619084", "R-HSA-5689896", "R-HSA-3371511", "R-HSA-6798695", "R-HSA-5387390", "R-HSA-3371556", "R-HSA-597592", "kegg_path:hsa05014", "R-HSA-9663891" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "P55072", "ensembl_id": "ENSG00000165280", "entrez_id": "7415", "chromosome_number": "9" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1703" }, { "type": "SmallVariant", "id": "2066" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/VCP/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/VCP/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "556" }, { "type": "GeneCombination", "id": "713" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/VCP/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/VCP/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/VCP/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.775850", "status": "CU", "curator": null, "submitter": "cnachteg" } }