Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/USH1C/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "79",
            "attributes": {
                "gene_relationship": [
                    "Directly interacting",
                    "Same protein complex",
                    "Involved in the same disease",
                    "Affecting the same tissue",
                    "Relevant pathways for phenotype",
                    "Same pathway",
                    "Co-expression"
                ],
                "protein_interactions": [
                    "(CDH23, USH1C)"
                ],
                "common_pathways": [],
                "genecomb_metascore": 2,
                "lastmodified": "2021-10-18T11:00:48.700124"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI104"
                        },
                        {
                            "type": "Combination",
                            "id": "OLI263"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/79/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/79/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "CDH23"
                        },
                        {
                            "type": "Gene",
                            "id": "USH1C"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/79/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/79/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/79/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "758",
            "attributes": {
                "gene_relationship": [
                    "Directly interacting",
                    "Relevant pathways for phenotype",
                    "Affecting the same tissue"
                ],
                "protein_interactions": [
                    "(MYO7A, USH1C)"
                ],
                "common_pathways": [],
                "genecomb_metascore": 2,
                "lastmodified": "2024-03-01T14:54:20.569539"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1037"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/758/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/758/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "MYO7A"
                        },
                        {
                            "type": "Gene",
                            "id": "USH1C"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/758/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/758/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/758/?format=api"
            }
        }
    ]
}