Gene Instance
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genes/TUBA4A/?format=api
{ "data": { "type": "Gene", "id": "TUBA4A", "attributes": { "go_molecular_function": [ "GTP binding", "protein kinase binding", "protein binding", "GTPase activity", "structural constituent of cytoskeleton" ], "pathway_id": [ "R-HSA-114608", "R-HSA-2500257", "R-HSA-3371497", "R-HSA-391251", "kegg_path:hsa05010", "kegg_path:hsa05020", "kegg_path:hsa04145", "kegg_path:hsa05012", "R-HSA-68877", "R-HSA-168256", "R-HSA-112314", "R-HSA-390466", "R-HSA-392499", "R-HSA-9609736", "R-HSA-8856688", "R-HSA-9675108", "R-HSA-422475", "R-HSA-112316", "R-HSA-1640170", "R-HSA-76005", "kegg_path:hsa05016", "kegg_path:hsa05014", "R-HSA-8854518", "R-HSA-597592", "R-HSA-5617833", "R-HSA-195258", "R-HSA-2467813", "R-HSA-1445148", "R-HSA-373760", "R-HSA-5653656", "R-HSA-2995410", "R-HSA-109582", "R-HSA-2565942", "R-HSA-9619483", "R-HSA-6807878", "R-HSA-5663220", "R-HSA-76002", "R-HSA-9668328", "R-HSA-442755", "R-HSA-5358351", "R-HSA-9646399", "R-HSA-199977", "R-HSA-380259", "R-HSA-389960", "R-HSA-389977", "R-HSA-1643685", "R-HSA-1280218", "R-HSA-438064", "R-HSA-68882", "R-HSA-1632852", "R-HSA-380284", "R-HSA-69275", "kegg_path:hsa05132", "R-HSA-190861", "R-HSA-199991", "R-HSA-2132295", "R-HSA-5663205", "R-HSA-1266738", "R-HSA-5620924", "R-HSA-9612973", "R-HSA-380270", "R-HSA-446203", "R-HSA-162582", "R-HSA-380287", "R-HSA-5610787", "R-HSA-5620912", "kegg_path:hsa04540", "R-HSA-983189", "R-HSA-389958", "R-HSA-8953897", "R-HSA-2262752", "R-HSA-389957", "kegg_path:hsa05022", "R-HSA-1852241", "R-HSA-437239", "R-HSA-190828", "R-HSA-983231", "R-HSA-6811442", "R-HSA-9648025", "R-HSA-157858", "R-HSA-948021", "R-HSA-2555396", "kegg_path:hsa04210", "kegg_path:hsa04530", "R-HSA-190840", "R-HSA-69278", "R-HSA-8852276", "R-HSA-6811436", "R-HSA-5626467", "R-HSA-68886", "R-HSA-194315", "R-HSA-6811434", "R-HSA-9609646", "kegg_path:hsa05130", "R-HSA-9663891", "R-HSA-8955332", "R-HSA-380320", "R-HSA-9609690", "R-HSA-112315", "R-HSA-453274", "R-HSA-190872" ], "essential_gene": null, "status": null, "uniprot_acc": "P68366", "ensembl_id": "ENSG00000127824", "entrez_id": "7277", "chromosome_number": "2" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2090" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TUBA4A/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TUBA4A/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "724" }, { "type": "GeneCombination", "id": "725" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TUBA4A/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TUBA4A/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TUBA4A/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2022-08-04T14:14:59.078114", "status": "CU", "curator": null, "submitter": "cnachteg" } }