Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/TTN/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "449", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 0.706847, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179544684, "genomic_position_hg38": 178679957, "chromosome": "2", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:43.146572", "ref_allele": "A", "alt_allele": "ACTT", "cdna_change": "c.32565_32566insAAG", "protein_change": "p.Glu10855_Tyr10856insLys", "transcript_id": "NM_001256850.1", "dbsnp_id": "rs1577324587", "variant_effect": "insertion" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI231" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/449/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/449/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/449/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/449/gene/?format=api" }, "data": { "type": "Gene", "id": "TTN" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/449/?format=api" } }, { "type": "SmallVariant", "id": "450", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 6.448e-05, "gnomad_AFR_maf": 6.463e-05, "gnomad_AMR_maf": 0.000116, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 5.591e-05, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 8.919e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0001219 }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.045188, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179444867, "genomic_position_hg38": 178580140, "chromosome": "2", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.152876", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.62224G>A", "protein_change": "p.Gly20742Arg", "transcript_id": "NM_001256850.1", "dbsnp_id": "rs372388682", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI231" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/450/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/450/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/450/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/450/gene/?format=api" }, "data": { "type": "Gene", "id": "TTN" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/450/?format=api" } }, { "type": "SmallVariant", "id": "452", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0016, "KGP_genomes_AFR_maf": 0.0008, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.002, "KGP_genomes_SAS_maf": 0.0051, "gnomad_maf": 0.004103, "gnomad_AFR_maf": 0.0006153, "gnomad_AMR_maf": 0.0006365, "gnomad_ASJ_maf": 0.001192, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.00966, "gnomad_NFE_maf": 0.005483, "gnomad_OTH_maf": 0.00294, "gnomad_SAS_maf": 0.004476, "ESP_AA_maf": 0.0009079, "ESP_EA_maf": 0.004419 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 2.765379, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179632598, "genomic_position_hg38": 178767871, "chromosome": "2", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.165367", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.9359G>A", "protein_change": "p.Arg3120Gln", "transcript_id": "NM_001256850.1", "dbsnp_id": "rs72647894", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI232" }, { "type": "Combination", "id": "OLI236" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/452/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/452/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/452/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/452/gene/?format=api" }, "data": { "type": "Gene", "id": "TTN" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/452/?format=api" } }, { "type": "SmallVariant", "id": "453", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0014, "KGP_genomes_AFR_maf": 0.0008, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.002, "KGP_genomes_SAS_maf": 0.0041, "gnomad_maf": 0.003745, "gnomad_AFR_maf": 0.0002583, "gnomad_AMR_maf": 0.0005219, "gnomad_ASJ_maf": 0.001194, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.009656, "gnomad_NFE_maf": 0.005252, "gnomad_OTH_maf": 0.002316, "gnomad_SAS_maf": 0.002745, "ESP_AA_maf": 0.0004946, "ESP_EA_maf": 0.004066 }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.26017, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179404550, "genomic_position_hg38": 178539823, "chromosome": "2", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.171509", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.93319C>T", "protein_change": "p.Arg31107Cys", "transcript_id": "NM_001256850.1", "dbsnp_id": "rs72648272", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI232" }, { "type": "Combination", "id": "OLI236" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/453/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/453/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/453/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/453/gene/?format=api" }, "data": { "type": "Gene", "id": "TTN" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/453/?format=api" } }, { "type": "SmallVariant", "id": "455", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 4.013e-06, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 8.852e-06, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 2.007465, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179571381, "genomic_position_hg38": 178706654, "chromosome": "2", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.188202", "ref_allele": "G", "alt_allele": "C", "cdna_change": "c.28269C>G", "protein_change": "p.Asn9423Lys", "transcript_id": "NM_001256850.1", "dbsnp_id": "rs371745586", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI233" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/455/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/455/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/455/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/455/gene/?format=api" }, "data": { "type": "Gene", "id": "TTN" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/455/?format=api" } }, { "type": "SmallVariant", "id": "462", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 3.983e-06, "gnomad_AFR_maf": 6.152e-05, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 2.238858, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179639081, "genomic_position_hg38": 178774354, "chromosome": "2", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.231870", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.6910G>A", "protein_change": "p.Val2304Met", "transcript_id": "NM_001256850.1", "dbsnp_id": "rs1412860664", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI237" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/462/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/462/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/462/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/462/gene/?format=api" }, "data": { "type": "Gene", "id": "TTN" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/462/?format=api" } }, { "type": "SmallVariant", "id": "463", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0022, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0014, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.008, "KGP_genomes_SAS_maf": 0.002, "gnomad_maf": 0.005113, "gnomad_AFR_maf": 0.001494, "gnomad_AMR_maf": 0.002134, "gnomad_ASJ_maf": 0.002999, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.008355, "gnomad_NFE_maf": 0.007792, "gnomad_OTH_maf": 0.005882, "gnomad_SAS_maf": 0.001707, "ESP_AA_maf": 0.0005482, "ESP_EA_maf": 0.008591 }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 2.370112, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179486037, "genomic_position_hg38": 178621310, "chromosome": "2", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.238168", "ref_allele": "C", "alt_allele": "A", "cdna_change": "c.40485G>T", "protein_change": "p.Lys13495Asn", "transcript_id": "NM_001256850.1", "dbsnp_id": "rs72677225", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI237" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/463/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/463/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/463/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/463/gene/?format=api" }, "data": { "type": "Gene", "id": "TTN" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/463/?format=api" } }, { "type": "SmallVariant", "id": "1451", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 4.436e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.000997, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 8.92e-06, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 2.304802, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179444910, "genomic_position_hg38": 178580183, "chromosome": "2", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:49.233578", "ref_allele": "T", "alt_allele": "G", "cdna_change": null, "protein_change": "p.Lys22368Asn", "transcript_id": "NM_001256850.1", "dbsnp_id": "rs727503577", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI672" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1451/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1451/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1451/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1451/gene/?format=api" }, "data": { "type": "Gene", "id": "TTN" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1451/?format=api" } }, { "type": "SmallVariant", "id": "2019", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0004, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.002, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 9.51e-05, "gnomad_AFR_maf": 0.0001977, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.001136, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.0002728, "ESP_EA_maf": 0.0 }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 2.770834, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179593070, "genomic_position_hg38": 178728343, "chromosome": "2", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:52.738023", "ref_allele": "A", "alt_allele": "C", "cdna_change": "c.19481T>G", "protein_change": "p.Leu6494Arg", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI933" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2019/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2019/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2019/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2019/gene/?format=api" }, "data": { "type": "Gene", "id": "TTN" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2019/?format=api" } }, { "type": "SmallVariant", "id": "2782", "attributes": { "frequencies": { "KGP_genomes_maf": 0.002, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0014, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.002, "KGP_genomes_SAS_maf": 0.0072, "gnomad_maf": 0.002682, "gnomad_AFR_maf": 0.0001296, "gnomad_AMR_maf": 0.0008198, "gnomad_ASJ_maf": 0.005684, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.001739, "gnomad_NFE_maf": 0.003288, "gnomad_OTH_maf": 0.002015, "gnomad_SAS_maf": 0.005274, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": "Damaging", "cadd_prediction": 2.546941, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 179414177, "genomic_position_hg38": 178549450, "chromosome": "2", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:57.210621", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.87253C>T", "protein_change": null, "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1326" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2782/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2782/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2782/relationships/gene_name?format=api", "related": 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