Gene Instance
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genes/TNFRSF1A/?format=api
{ "data": { "type": "Gene", "id": "TNFRSF1A", "attributes": { "go_molecular_function": [ "['tumor necrosis factor binding', 'tumor necrosis factor-activated receptor activity', 'protein binding']" ], "pathway_id": [ "kegg_path:hsa04010", "kegg_path:hsa04060", "kegg_path:hsa04061", "kegg_path:hsa04064", "kegg_path:hsa04071", "kegg_path:hsa04150", "kegg_path:hsa04210", "kegg_path:hsa04215", "kegg_path:hsa04217", "kegg_path:hsa04380", "kegg_path:hsa04668", "kegg_path:hsa04920", "kegg_path:hsa04931", "kegg_path:hsa04932", "kegg_path:hsa05010", "kegg_path:hsa05014", "kegg_path:hsa05022", "kegg_path:hsa05130", "kegg_path:hsa05131", "kegg_path:hsa05132", "kegg_path:hsa05142", "kegg_path:hsa05145", "kegg_path:hsa05152", "kegg_path:hsa05160", "kegg_path:hsa05163", "kegg_path:hsa05164", "kegg_path:hsa05165", "kegg_path:hsa05166", "kegg_path:hsa05167", "kegg_path:hsa05168", "kegg_path:hsa05170", "kegg_path:hsa05171", "kegg_path:hsa05418", "R-HSA-1280215", "R-HSA-162582", "R-HSA-168256", "R-HSA-449147", "R-HSA-5357786", "R-HSA-5357905", "R-HSA-5357956", "R-HSA-5626978", "R-HSA-5668541", "R-HSA-5669034", "R-HSA-6783783", "R-HSA-73887", "R-HSA-75893" ], "essential_gene": "Non-essential", "status": null, "uniprot_acc": "P19438", "ensembl_id": "None", "entrez_id": "ENSG00000067182", "chromosome_number": "12" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "887" }, { "type": "SmallVariant", "id": "3739" }, { "type": "SmallVariant", "id": "3742" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TNFRSF1A/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TNFRSF1A/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 5 }, "data": [ { "type": "GeneCombination", "id": "275" }, { "type": "GeneCombination", "id": "1260" }, { "type": "GeneCombination", "id": "1261" }, { "type": "GeneCombination", "id": "1265" }, { "type": "GeneCombination", "id": "1266" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TNFRSF1A/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TNFRSF1A/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TNFRSF1A/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.563991", "status": "CU", "curator": null, "submitter": "cnachteg" } }