Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/TG/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "67", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 4.910688, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 133953594, "genomic_position_hg38": 132941349, "chromosome": "8", "annotation_flag": "automatically_attributed_and_verified", "lastmodified": "2023-06-06T16:57:40.918253", "ref_allele": "A", "alt_allele": "G", "cdna_change": "c.5042-2A>G", "protein_change": null, "transcript_id": "NM_003235.4", "dbsnp_id": "NA", "variant_effect": "splicing" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI031" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/67/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/67/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/67/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/67/gene/?format=api" }, "data": { "type": "Gene", "id": "TG" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/67/?format=api" } }, { "type": "SmallVariant", "id": "1000", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0002, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.001, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.0001512, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.002068, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 1.710226, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 133885463, "genomic_position_hg38": 132873218, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:46.512378", "ref_allele": "A", "alt_allele": "G", "cdna_change": null, "protein_change": "p.Asn212Ser", "transcript_id": null, "dbsnp_id": "rs187737243", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI466" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1000/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1000/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1000/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1000/gene/?format=api" }, "data": { "type": "Gene", "id": "TG" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1000/?format=api" } }, { "type": "SmallVariant", "id": "1001", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0014, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0069, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.0004991, "gnomad_AFR_maf": 0.0004322, "gnomad_AMR_maf": 8.699e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.005136, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 9.722e-05, "gnomad_OTH_maf": 0.0004899, "gnomad_SAS_maf": 0.0002293, "ESP_AA_maf": 0.0006809, "ESP_EA_maf": 0.0 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.792371, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 134125846, "genomic_position_hg38": 133113602, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:46.518432", "ref_allele": "C", "alt_allele": "T", "cdna_change": null, "protein_change": "p.Arg2585Trp", "transcript_id": null, "dbsnp_id": "rs114211101", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI467" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1001/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1001/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1001/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1001/gene/?format=api" }, "data": { "type": "Gene", "id": "TG" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1001/?format=api" } }, { "type": "SmallVariant", "id": "1004", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0008, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.004, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.0002034, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.002507, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0001634, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": -0.162228, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 133980143, "genomic_position_hg38": 132967898, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:46.536805", "ref_allele": "A", "alt_allele": "G", "cdna_change": null, "protein_change": "p.Ile1931Val", "transcript_id": null, "dbsnp_id": "rs115877910", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI468" }, { "type": "Combination", "id": "OLI469" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1004/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1004/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1004/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1004/gene/?format=api" }, "data": { "type": "Gene", "id": "TG" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1004/?format=api" } }, { "type": "SmallVariant", "id": "1007", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 3.977e-06, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 5.437e-05, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 4.517447, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 133906036, "genomic_position_hg38": 132893791, "chromosome": "8", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:46.554858", "ref_allele": "GA", "alt_allele": "G", "cdna_change": "c.2864delA", "protein_change": "Glu955GlyfsTer11", "transcript_id": "NM_003235.5", "dbsnp_id": "rs1563920665", "variant_effect": "frameshift" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI469" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1007/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1007/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1007/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1007/gene/?format=api" }, "data": { "type": "Gene", "id": "TG" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1007/?format=api" } }, { "type": "SmallVariant", "id": "1008", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 7.953e-06, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 2.891e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 3.266e-05, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 5.111739, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 134031903, "genomic_position_hg38": 133019658, "chromosome": "8", "annotation_flag": "manually_corrected", "lastmodified": "2023-06-06T16:57:46.560905", "ref_allele": "ATTGT", "alt_allele": "A", "cdna_change": "c.6844_6847del", "protein_change": "p.Leu2282IlefsTer61", "transcript_id": "NM_003235.4", "dbsnp_id": "rs774153375", "variant_effect": "frameshift" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI469" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1008/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1008/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1008/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1008/gene/?format=api" }, "data": { "type": "Gene", "id": "TG" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1008/?format=api" } }, { "type": "SmallVariant", "id": "1009", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0004, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.002, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.0001233, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.001305, "gnomad_FIN_maf": 4.62e-05, "gnomad_NFE_maf": 4.397e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 3.266e-05, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": -0.674439, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 133953766, "genomic_position_hg38": 132941521, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:46.566958", "ref_allele": "G", "alt_allele": "A", "cdna_change": null, "protein_change": "p.Val1738Ile", "transcript_id": null, "dbsnp_id": "rs115053637", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI470" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1009/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1009/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1009/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1009/gene/?format=api" }, "data": { "type": "Gene", "id": "TG" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1009/?format=api" } }, { "type": "SmallVariant", "id": "1010", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 3.988e-06, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 8.829e-06, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": -0.475252, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 133980087, "genomic_position_hg38": 132967842, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:46.572896", "ref_allele": "G", "alt_allele": "A", "cdna_change": null, "protein_change": "p.Ser1912Asn", "transcript_id": null, "dbsnp_id": "rs762807254", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI470" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1010/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1010/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1010/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1010/gene/?format=api" }, "data": { "type": "Gene", "id": "TG" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1010/?format=api" } }, { "type": "SmallVariant", "id": "1019", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0004, "KGP_genomes_AFR_maf": 0.0008, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.001, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 5.704e-05, "gnomad_AFR_maf": 0.0001235, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0006535, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.0004539, "ESP_EA_maf": 0.0 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.747572, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 133900739, "genomic_position_hg38": 132888494, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:46.627149", "ref_allele": "G", "alt_allele": "A", "cdna_change": null, "protein_change": "p.Arg896Gln", "transcript_id": null, "dbsnp_id": "rs374707675", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI474" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1019/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1019/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1019/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1019/gene/?format=api" }, "data": { "type": "Gene", "id": "TG" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1019/?format=api" } }, { "type": "SmallVariant", "id": "1100", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 1.85988, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 133961157, "genomic_position_hg38": 132948912, "chromosome": "8", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:47.131677", "ref_allele": "AT", "alt_allele": "A", "cdna_change": "c.5372delT", "protein_change": "p.Leu1791CysfsTer12", "transcript_id": "NM_003235", "dbsnp_id": "NA", "variant_effect": "frameshift" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI519" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1100/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1100/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1100/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1100/gene/?format=api" }, "data": { "type": "Gene", "id": "TG" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1100/?format=api" } }, 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