Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/SLIT1/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "1250",
            "attributes": {
                "gene_relationship": [
                    "Monogenic experiments only",
                    "Affecting the same tissue",
                    "Relevant pathways for phenotype",
                    "Involved in the same disease",
                    "Same pathway"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 2,
                "lastmodified": "2024-03-01T14:30:07.976392"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1743"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1250/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1250/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "ROBO4"
                        },
                        {
                            "type": "Gene",
                            "id": "SLIT1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1250/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1250/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/1250/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "1251",
            "attributes": {
                "gene_relationship": [
                    "Monogenic experiments only",
                    "Affecting the same tissue",
                    "Relevant pathways for phenotype",
                    "Same pathway"
                ],
                "protein_interactions": [],
                "common_pathways": [
                    "Signaling by ROBO receptors",
                    "Regulation of expression of SLITs and ROBOs",
                    "Regulation of commissural axon pathfinding by SLIT and ROBO",
                    "Nervous system development",
                    "Netrin-1 signaling",
                    "Axon guidance",
                    "Developmental Biology"
                ],
                "genecomb_metascore": 2,
                "lastmodified": "2024-03-01T14:29:49.225512"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1744"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1251/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1251/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "SLIT1"
                        },
                        {
                            "type": "Gene",
                            "id": "SLIT2"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1251/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1251/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/1251/?format=api"
            }
        }
    ]
}