Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/SETX/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "528", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0026, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0086, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.007, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.003909, "gnomad_AFR_maf": 0.001046, "gnomad_AMR_maf": 0.006302, "gnomad_ASJ_maf": 0.001091, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0003234, "gnomad_NFE_maf": 0.005722, "gnomad_OTH_maf": 0.007818, "gnomad_SAS_maf": 0.001013, "ESP_AA_maf": 0.0009079, "ESP_EA_maf": 0.007674 }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": -0.174818, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 135140020, "genomic_position_hg38": 132264633, "chromosome": "9", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.636352", "ref_allele": "A", "alt_allele": "G", "cdna_change": "c.7640T>C", "protein_change": "p.Ile2547Thr", "transcript_id": "NM_015046.5", "dbsnp_id": "rs151117904", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 5 }, "data": [ { "type": "Combination", "id": "OLI270" }, { "type": "Combination", "id": "OLI273" }, { "type": "Combination", "id": "OLI276" }, { "type": "Combination", "id": "OLI282" }, { "type": "Combination", "id": "OLI661" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/528/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/528/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/528/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/528/gene/?format=api" }, "data": { "type": "Gene", "id": "SETX" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/528/?format=api" } }, { "type": "SmallVariant", "id": "538", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 0.0002187, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0003968, "gnomad_EAS_maf": 5.437e-05, "gnomad_FIN_maf": 0.0001848, "gnomad_NFE_maf": 0.0004045, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0001163 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.525222, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 135206706, "genomic_position_hg38": 132331319, "chromosome": "9", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.682441", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.968G>A", "protein_change": "p.Ser323Asn", "transcript_id": "NM_015046.5", "dbsnp_id": "rs372193033", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI277" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/538/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/538/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/538/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/538/gene/?format=api" }, "data": { "type": "Gene", "id": "SETX" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/538/?format=api" } }, { "type": "SmallVariant", "id": "544", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 3.182e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 4.396e-05, "gnomad_OTH_maf": 0.000163, "gnomad_SAS_maf": 6.533e-05, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.417659, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 135210013, "genomic_position_hg38": 132334626, "chromosome": "9", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.716509", "ref_allele": "T", "alt_allele": "C", "cdna_change": "c.820A>G", "protein_change": "p.Met274Val", "transcript_id": "NM_015046.5", "dbsnp_id": "rs753713810", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI281" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/544/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/544/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/544/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/544/gene/?format=api" }, "data": { "type": "Gene", "id": "SETX" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/544/?format=api" } }, { "type": "SmallVariant", "id": "546", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 3.976e-06, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 8.79e-06, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 3.005102, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 135224775, "genomic_position_hg38": 132349388, "chromosome": "9", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.727242", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.41C>T", "protein_change": "p.Thr14Ile", "transcript_id": "NM_015046.5", "dbsnp_id": "rs770310239", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI282" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/546/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/546/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/546/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/546/gene/?format=api" }, "data": { "type": "Gene", "id": "SETX" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/546/?format=api" } }, { "type": "SmallVariant", "id": "547", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0058, "KGP_genomes_AFR_maf": 0.0008, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.004, "KGP_genomes_EUR_maf": 0.002, "KGP_genomes_SAS_maf": 0.0225, "gnomad_maf": 0.005494, "gnomad_AFR_maf": 0.0004314, "gnomad_AMR_maf": 0.0005205, "gnomad_ASJ_maf": 0.000298, "gnomad_EAS_maf": 0.002719, "gnomad_FIN_maf": 0.00753, "gnomad_NFE_maf": 0.003519, "gnomad_OTH_maf": 0.003429, "gnomad_SAS_maf": 0.02346, "ESP_AA_maf": 0.0006809, "ESP_EA_maf": 0.004419 }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.50487, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 135202325, "genomic_position_hg38": 132326938, "chromosome": "9", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:43.732802", "ref_allele": "A", "alt_allele": "C", "cdna_change": "c.4660T>G", "protein_change": "p.Cys1554Gly", "transcript_id": "NM_015046.5", "dbsnp_id": "rs112089123", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI283" }, { "type": "Combination", "id": "OLI663" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/547/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/547/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/547/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/547/gene/?format=api" }, "data": { "type": "Gene", "id": "SETX" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/547/?format=api" } }, { "type": "SmallVariant", "id": "921", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": -1.4259, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 135139703, "genomic_position_hg38": 132264316, "chromosome": "9", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:46.033742", "ref_allele": "T", "alt_allele": "C", "cdna_change": "c.7957A>G", "protein_change": "p.Thr2653Ala", "transcript_id": "NM_015046.5", "dbsnp_id": "rs1842517067", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI431" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/921/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/921/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/921/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/921/gene/?format=api" }, "data": { "type": "Gene", "id": "SETX" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/921/?format=api" } }, { "type": "SmallVariant", "id": "929", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0084, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0144, "KGP_genomes_EAS_maf": 0.0179, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0143, "gnomad_maf": 0.006093, "gnomad_AFR_maf": 0.0003076, "gnomad_AMR_maf": 0.02781, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.01903, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 7.912e-05, "gnomad_OTH_maf": 0.004886, "gnomad_SAS_maf": 0.005749, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0001163 }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.98701, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 135147182, "genomic_position_hg38": 132271795, "chromosome": "9", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:46.085933", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.7114C>T", "protein_change": "p.Asp2372Asn", "transcript_id": null, "dbsnp_id": "rs150673589", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI435" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/929/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/929/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/929/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/929/gene/?format=api" }, "data": { "type": "Gene", "id": "SETX" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/929/?format=api" } }, { "type": "SmallVariant", "id": "1381", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0066, "KGP_genomes_AFR_maf": 0.0015, "KGP_genomes_AMR_maf": 0.0101, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0179, "KGP_genomes_SAS_maf": 0.0061, "gnomad_maf": 0.01522, "gnomad_AFR_maf": 0.002405, "gnomad_AMR_maf": 0.007781, "gnomad_ASJ_maf": 0.007469, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.05052, "gnomad_NFE_maf": 0.01774, "gnomad_OTH_maf": 0.01542, "gnomad_SAS_maf": 0.007873, "ESP_AA_maf": 0.002724, "ESP_EA_maf": 0.01628 }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 0.4458, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 135204010, "genomic_position_hg38": 132328623, "chromosome": "9", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:48.757538", "ref_allele": "T", "alt_allele": "C", "cdna_change": "c.2975A>G", "protein_change": "p.Lys992Arg", "transcript_id": "NM_015046.5", "dbsnp_id": "rs61742937", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI635" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1381/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1381/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1381/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1381/gene/?format=api" }, "data": { "type": "Gene", "id": "SETX" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1381/?format=api" } }, { "type": "SmallVariant", "id": "1425", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 7.952e-06, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 1.758e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 0.74006, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 135140098, "genomic_position_hg38": 132264711, "chromosome": "9", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:49.057611", "ref_allele": "G", "alt_allele": "A", "cdna_change": null, "protein_change": "p.Thr2521Ile", "transcript_id": null, "dbsnp_id": "rs760854140", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI655" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1425/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1425/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1425/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1425/gene/?format=api" }, "data": { "type": "Gene", "id": "SETX" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1425/?format=api" } }, { "type": "SmallVariant", "id": "1431", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0008, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.002, "KGP_genomes_SAS_maf": 0.002, "gnomad_maf": 0.001251, "gnomad_AFR_maf": 0.0001231, "gnomad_AMR_maf": 0.001302, "gnomad_ASJ_maf": 0.004169, "gnomad_EAS_maf": 0.0001087, "gnomad_FIN_maf": 0.0001389, "gnomad_NFE_maf": 0.001251, "gnomad_OTH_maf": 0.0009804, "gnomad_SAS_maf": 0.002353, "ESP_AA_maf": 0.0002271, "ESP_EA_maf": 0.0009302 }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 2.29924, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 135203756, "genomic_position_hg38": 132328369, "chromosome": "9", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:49.098068", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.3229G>A", "protein_change": "p.Asp1077Asn", "transcript_id": "NM_015046.5", "dbsnp_id": "rs145097270", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI659" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1431/relationships/in_combination?format=api", "related": 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